ID   3.6.1.66
DE   XTP/dITP diphosphatase.
AN   hypoxanthine/xanthine dNTP pyrophosphatase.
CA   (1) H2O + XTP = diphosphate + H(+) + XMP.
CA   (2) dITP + H2O = dIMP + diphosphate + H(+).
CA   (3) H2O + ITP = diphosphate + H(+) + IMP.
CC   -!- The enzymes from the bacterium Escherichia coli and the archaea
CC       Methanococcus jannaschii and Archaeoglobus fulgidus are highly
CC       specific for XTP, dITP and ITP.
DR   A9NGK2, IXTPA_ACHLI;  Q6FEQ6, IXTPA_ACIAD;  B7H0A1, IXTPA_ACIB3;
DR   B7I4X1, IXTPA_ACIB5;  B2I3B3, IXTPA_ACIBC;  A3M1X9, IXTPA_ACIBT;
DR   C1F8I0, IXTPA_ACIC5;  B9MEJ9, IXTPA_ACIET;  A1W4I7, IXTPA_ACISJ;
DR   Q8UIG9, IXTPA_AGRFC;  Q21XZ3, IXTPA_ALBFT;  A8ESC9, IXTPA_ALIB4;
DR   Q2IEX2, IXTPA_ANADE;  A7HFW2, IXTPA_ANADF;  O66580, IXTPA_AQUAE;
DR   O28046, IXTPA_ARCFU;  Q5P5J5, IXTPA_AROAE;  Q81LB0, IXTPA_BACAN;
DR   Q72ZT2, IXTPA_BACC1;  Q817P4, IXTPA_BACCR;  Q633V5, IXTPA_BACCZ;
DR   Q64MG2, IXTPA_BACFR;  Q6HD43, IXTPA_BACHK;  Q65GG3, IXTPA_BACLD;
DR   P94558, IXTPA_BACSU;  Q8A327, IXTPA_BACTN;  Q6G565, IXTPA_BARHE;
DR   Q6G1E6, IXTPA_BARQU;  Q6MJR8, IXTPA_BDEBA;  B8DVS6, IXTPA_BIFA0;
DR   B3DTK7, IXTPA_BIFLD;  Q8G7I1, IXTPA_BIFLO;  B7GN27, IXTPA_BIFLS;
DR   Q0SNR4, IXTPA_BORAP;  Q7WI95, IXTPA_BORBR;  O51263, IXTPA_BORBU;
DR   B7J1H5, IXTPA_BORBZ;  B5RL72, IXTPA_BORDL;  Q662B8, IXTPA_BORGP;
DR   Q7W6C6, IXTPA_BORPA;  Q7VXX8, IXTPA_BORPE;  B5RR63, IXTPA_BORRA;
DR   Q89WK5, IXTPA_BRADU;  A5E8I8, IXTPA_BRASB;  P64305, IXTPA_BRUME;
DR   P64306, IXTPA_BRUSU;  Q62HZ7, IXTPA_BURMA;  Q63RV4, IXTPA_BURPS;
DR   Q8RC29, IXTPA_CALS4;  A7ZBP3, IXTPA_CAMC1;  A0RMP5, IXTPA_CAMFF;
DR   A7HZE0, IXTPA_CAMHC;  A8FN54, IXTPA_CAMJ8;  A7H1W5, IXTPA_CAMJD;
DR   Q9PMS6, IXTPA_CAMJE;  A1W0Z2, IXTPA_CAMJJ;  Q5HT36, IXTPA_CAMJR;
DR   Q9ABS4, IXTPA_CAUVC;  Q5L4Q6, IXTPA_CHLAB;  Q821F9, IXTPA_CHLCV;
DR   Q256I5, IXTPA_CHLFF;  Q9PJD4, IXTPA_CHLMU;  Q9Z7D1, IXTPA_CHLPN;
DR   B0B8I0, IXTPA_CHLT2;  Q3KL90, IXTPA_CHLTA;  B0BA59, IXTPA_CHLTB;
DR   Q8KFJ6, IXTPA_CHLTE;  O84611, IXTPA_CHLTR;  A0M0C9, IXTPA_CHRFK;
DR   Q7NZJ6, IXTPA_CHRVO;  Q97FR2, IXTPA_CLOAB;  Q8XI68, IXTPA_CLOPE;
DR   Q891I4, IXTPA_CLOTE;  Q6NFN7, IXTPA_CORDI;  Q8FMU9, IXTPA_COREF;
DR   A4QGQ5, IXTPA_CORGB;  Q8NMR5, IXTPA_CORGL;  Q4JX01, IXTPA_CORJK;
DR   B1VGW8, IXTPA_CORU7;  Q83FA3, IXTPA_COXBU;  Q6A760, IXTPA_CUTAK;
DR   C1CXX6, IXTPA_DEIDV;  Q1IW81, IXTPA_DEIGD;  Q9RXX6, IXTPA_DEIRA;
DR   A9BTA7, IXTPA_DELAS;  Q6AQD7, IXTPA_DESPS;  A4J7Y6, IXTPA_DESRM;
DR   Q726F4, IXTPA_DESVH;  B5YEU3, IXTPA_DICT6;  Q8XCU5, IXTPA_ECO57;
DR   Q8FE27, IXTPA_ECOL6;  P52061, IXTPA_ECOLI;  B2KEA9, IXTPA_ELUMP;
DR   B2VEZ3, IXTPA_ERWT9;  B1YJW5, IXTPA_EXIS2;  C4L4I7, IXTPA_EXISA;
DR   A5FH89, IXTPA_FLAJ1;  A6H0L2, IXTPA_FLAPJ;  Q0RQL6, IXTPA_FRAAA;
DR   Q5NEQ9, IXTPA_FRATT;  Q5KWI6, IXTPA_GEOKA;  Q74C80, IXTPA_GEOSL;
DR   Q7NN81, IXTPA_GLOVI;  Q5FRF4, IXTPA_GLUOX;  Q7VLS3, IXTPA_HAEDU;
DR   P44598, IXTPA_HAEIN;  Q9K8D9, IXTPA_HALH5;  A1WVN6, IXTPA_HALHL;
DR   Q7VF43, IXTPA_HELHP;  B4U8R9, IXTPA_HYDS0;  A2BJY7, IXTPA_HYPBU;
DR   Q5QY51, IXTPA_IDILO;  A8A8W1, IXTPA_IGNH4;  B1L6T7, IXTPA_KORCO;
DR   Q5FLV7, IXTPA_LACAC;  Q74KU4, IXTPA_LACJO;  Q9CG29, IXTPA_LACLA;
DR   Q88V20, IXTPA_LACPL;  Q5X245, IXTPA_LEGPA;  Q5ZSN3, IXTPA_LEGPH;
DR   Q5WTW9, IXTPA_LEGPL;  Q6AEL0, IXTPA_LEIXX;  B0SE38, IXTPA_LEPBA;
DR   B1Y0J8, IXTPA_LEPCP;  Q72UV8, IXTPA_LEPIC;  Q8F031, IXTPA_LEPIN;
DR   Q03YJ8, IXTPA_LEUMM;  Q92CH0, IXTPA_LISIN;  Q720J0, IXTPA_LISMF;
DR   Q8Y7N5, IXTPA_LISMO;  Q8EVN6, IXTPA_MALP2;  Q65RQ6, IXTPA_MANSM;
DR   Q8TJS1, IXTPA_METAC;  Q602P0, IXTPA_METCA;  B3DV19, IXTPA_METI4;
DR   Q57679, IXTPA_METJA;  Q8TV07, IXTPA_METKA;  Q8PZ91, IXTPA_METMA;
DR   A2SJB9, IXTPA_METPP;  D9PYS9, IXTPA_METTM;  B1MLZ4, IXTPA_MYCA9;
DR   P64308, IXTPA_MYCBO;  P52063, IXTPA_MYCLE;  Q6MT00, IXTPA_MYCMS;
DR   Q73X89, IXTPA_MYCPA;  P9WMR6, IXTPA_MYCTO;  P9WMR7, IXTPA_MYCTU;
DR   B2A6I7, IXTPA_NATTJ;  B9L638, IXTPA_NAUPA;  Q9JVG5, IXTPA_NEIMA;
DR   Q9K0G6, IXTPA_NEIMB;  Q82XJ3, IXTPA_NITEU;  A6Q5H7, IXTPA_NITSB;
DR   Q5Z0V0, IXTPA_NOCFA;  Q8YM52, IXTPA_NOSS1;  Q8EPJ6, IXTPA_OCEIH;
DR   B1ZXD5, IXTPA_OPITP;  A1TT41, IXTPA_PARC0;  A6LGA4, IXTPA_PARD8;
DR   Q7U9M0, IXTPA_PARMW;  Q6MF40, IXTPA_PARUW;  Q9CKF5, IXTPA_PASMU;
DR   Q6D117, IXTPA_PECAS;  Q7N7H2, IXTPA_PHOLL;  Q6LML4, IXTPA_PHOPR;
DR   Q6L1H9, IXTPA_PICTO;  A1VKF6, IXTPA_POLNA;  Q7MUC6, IXTPA_PORGI;
DR   A2C0B3, IXTPA_PROM1;  Q7VDQ7, IXTPA_PROMA;  Q7V4S3, IXTPA_PROMM;
DR   Q7V316, IXTPA_PROMP;  Q46H95, IXTPA_PROMT;  Q9I6A8, IXTPA_PSEAE;
DR   Q88CT0, IXTPA_PSEPK;  Q87V88, IXTPA_PSESM;  Q8ZVB5, IXTPA_PYRAE;
DR   Q8U446, IXTPA_PYRFU;  O59580, IXTPA_PYRHO;  Q8XXF4, IXTPA_RALN1;
DR   Q98DN4, IXTPA_RHILO;  Q92SK4, IXTPA_RHIME;  Q7UGM3, IXTPA_RHOBA;
DR   B6IVK5, IXTPA_RHOCS;  Q6NCY9, IXTPA_RHOPA;  Q2RN61, IXTPA_RHORT;
DR   Q5LWF7, IXTPA_RUEPO;  Q97ZZ0, IXTPA_SACS2;  Q5PMK9, IXTPA_SALPA;
DR   Q8Z3U6, IXTPA_SALTI;  Q8ZM45, IXTPA_SALTY;  Q8EBY7, IXTPA_SHEON;
DR   Q83JS0, IXTPA_SHIFL;  Q5WEM4, IXTPA_SHOC1;  Q5HGT2, IXTPA_STAAC;
DR   P64309, IXTPA_STAAM;  P99094, IXTPA_STAAN;  Q6GHT4, IXTPA_STAAR;
DR   Q6GA63, IXTPA_STAAS;  P58995, IXTPA_STAAW;  Q5HQ23, IXTPA_STAEQ;
DR   Q8CSY5, IXTPA_STAES;  Q8E3V8, IXTPA_STRA3;  Q8DY93, IXTPA_STRA5;
DR   Q82D15, IXTPA_STRAW;  Q9S2H9, IXTPA_STRCO;  Q8DSQ6, IXTPA_STRMU;
DR   Q9A1B6, IXTPA_STRP1;  P0DB58, IXTPA_STRP3;  Q5XDP8, IXTPA_STRP6;
DR   Q8P2D2, IXTPA_STRP8;  P64310, IXTPA_STRPN;  P0DB59, IXTPA_STRPQ;
DR   P64311, IXTPA_STRR6;  Q5M1I4, IXTPA_STRT1;  Q5M626, IXTPA_STRT2;
DR   Q30UH9, IXTPA_SULDN;  A6Q6L9, IXTPA_SULNB;  B2V8P5, IXTPA_SULSY;
DR   Q67SL4, IXTPA_SYMTH;  Q3A2Y7, IXTPA_SYNC1;  A0LG38, IXTPA_SYNFM;
DR   Q0IDG4, IXTPA_SYNS3;  P74432, IXTPA_SYNY3;  Q9HLA4, IXTPA_THEAC;
DR   Q5JEX8, IXTPA_THEKO;  Q9WY06, IXTPA_THEMA;  A5IKR2, IXTPA_THEP1;
DR   B0KBM4, IXTPA_THEP3;  B0K3T5, IXTPA_THEPX;  Q72I42, IXTPA_THET2;
DR   Q5SHS6, IXTPA_THET8;  Q8DHZ6, IXTPA_THEVB;  B5YHP2, IXTPA_THEYD;
DR   B8GPB3, IXTPA_THISH;  Q73KE7, IXTPA_TREDE;  O83452, IXTPA_TREPA;
DR   B2S334, IXTPA_TREPS;  Q83HF7, IXTPA_TROW8;  Q83FT2, IXTPA_TROWT;
DR   A1WQF4, IXTPA_VEREI;  Q9KUQ9, IXTPA_VIBCH;  Q87LJ1, IXTPA_VIBPA;
DR   Q8DCB9, IXTPA_VIBVU;  Q7MHJ0, IXTPA_VIBVY;  Q8D3C3, IXTPA_WIGBR;
DR   Q7MR19, IXTPA_WOLSU;  Q8PH61, IXTPA_XANAC;  Q4UY37, IXTPA_XANC8;
DR   Q8P5T3, IXTPA_XANCP;  Q5H3S6, IXTPA_XANOR;  Q9PD73, IXTPA_XYLFA;
DR   Q87DG2, IXTPA_XYLFT;  Q8ZHF4, IXTPA_YERPE;  Q666N1, IXTPA_YERPS;
DR   Q5NRL7, IXTPA_ZYMMO;
//