ENZYME entry: EC 3.6.3.49

Accepted Name
Channel-conductance-controlling ATPase.
Alternative Name(s)
Cystic-fibrosis membrane-conductance-regulating protein.
Reaction catalysed
ATP + H(2)O <=> ADP + phosphate
Comment(s)
  • An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis.
  • It is also involved in the functioning of other transmembrane channels.
Cross-references
PROSITEPDOC00185
BRENDA3.6.3.49
EC2PDB3.6.3.49
ExplorEnz3.6.3.49
PRIAM enzyme-specific profiles3.6.3.49
KEGG Ligand Database for Enzyme Nomenclature3.6.3.49
IUBMB Enzyme Nomenclature3.6.3.49
IntEnz3.6.3.49
MEDLINEFind literature relating to 3.6.3.49
MetaCyc3.6.3.49
UniProtKB/Swiss-Prot
Q07DV2, CFTR_AOTNA;  Q00PJ2, CFTR_ATEAB;  Q09YK5, CFTR_ATEGE;  
P35071, CFTR_BOVIN;  Q2QLF9, CFTR_CALJA;  Q2QLB4, CFTR_CALMO;  
Q5U820, CFTR_CANFA;  Q2QLC5, CFTR_CARPS;  Q00552, CFTR_CAVPO;  
Q2IBA1, CFTR_CHLAE;  Q07DY5, CFTR_COLGU;  Q07E42, CFTR_DASNO;  
Q2QL74, CFTR_DIDVI;  Q2IBF6, CFTR_GORGO;  Q2QLA3, CFTR_HORSE;  
P13569, CFTR_HUMAN;  Q108U0, CFTR_LOXAF;  Q7JII8, CFTR_MACFA;  
Q7JII7, CFTR_MACFU;  Q00553, CFTR_MACMU;  Q9TUQ2, CFTR_MACNE;  
Q2QL83, CFTR_MICMU;  P26361, CFTR_MOUSE;  Q09YJ4, CFTR_MUNMU;  
Q07DW5, CFTR_MUNRE;  Q07E16, CFTR_MUSPF;  Q07DX5, CFTR_NOMLE;  
Q07DZ6, CFTR_ORNAN;  Q2QLH0, CFTR_OTOGA;  Q2QLE5, CFTR_PANTR;  
Q9TSP5, CFTR_PAPAN;  Q6PQZ2, CFTR_PIG;  Q2IBE4, CFTR_PONAB;  
Q00554, CFTR_RABIT;  P34158, CFTR_RAT;  Q2IBB3, CFTR_RHIFE;  
Q09YH0, CFTR_SAIBB;  Q00555, CFTR_SHEEP;  P26362, CFTR_SQUAC;  
Q5D1Z7, CFTR_TRIVU;  P26363, CFTR_XENLA;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
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