ENZYME entry: EC 3.6.3.51

Accepted Name
Mitochondrial protein-transporting ATPase.
Reaction catalysed
ATP + H(2)O <=> ADP + phosphate
Comment(s)
  • A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase involved in the transport of proteins or preproteins into mitochondria using the TIM protein complex.
  • TIM is the protein transport machinery of the inner mitochondrial membrane that contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.
Cross-references
BRENDA3.6.3.51
EC2PDB3.6.3.51
ExplorEnz3.6.3.51
PRIAM enzyme-specific profiles3.6.3.51
KEGG Ligand Database for Enzyme Nomenclature3.6.3.51
IUBMB Enzyme Nomenclature3.6.3.51
IntEnz3.6.3.51
MEDLINEFind literature relating to 3.6.3.51
MetaCyc3.6.3.51

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.3.-
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-