ENZYME entry: EC 3.6.4.6
| Accepted Name |
|---|
| Vesicle-fusing ATPase.
|
| Reaction catalysed |
|---|
| ATP + H(2)O <=> ADP + phosphate |
| Comment(s) |
|---|
- A large family of ATP-hydrolyzing enzymes involved in the heterotypic
fusion of membrane vesicles with target membranes and the homotypic
fusion of various membrane compartments.
- They belong to the AAA-type (ATPase associated with a variety of cell
activities) ATPase superfamily.
- They include peroxin, which apparently is involved in Zellweger's
syndrome.
|
| Cross-references |
|---|
| PROSITE | PDOC00572 |
| BRENDA | 3.6.4.6 |
| EC2PDB | 3.6.4.6 |
| ExplorEnz | 3.6.4.6 |
| PRIAM enzyme-specific profiles | 3.6.4.6 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.6.4.6 |
| IUBMB Enzyme Nomenclature | 3.6.4.6 |
| IntEnz | 3.6.4.6 |
| MEDLINE | Find literature relating to 3.6.4.6 |
| MetaCyc | 3.6.4.6 |
| UniProtKB/Swiss-Prot |
| P46461, NSF1_DROME; | P54351, NSF2_DROME; | Q9M0Y8, NSF_ARATH; |
| Q94392, NSF_CAEEL; | P18708, NSF_CRIGR; | Q75JI3, NSF_DICDI; |
| P46459, NSF_HUMAN; | P46460, NSF_MOUSE; | Q5R410, NSF_PONAB; |
| Q9QUL6, NSF_RAT; | Q3ZBT1, TERA_BOVIN; | Q7ZU99, TERA_DANRE; |
| Q7KN62, TERA_DROME; | P55072, TERA_HUMAN; | Q01853, TERA_MOUSE; |
| P03974, TERA_PIG; | P46462, TERA_RAT; | P23787, TERA_XENLA; |
| Q6GL04, TERA_XENTR; | Q9UN37, VPS4A_HUMAN; | Q8VEJ9, VPS4A_MOUSE; |
| Q793F9, VPS4A_RAT; | Q0VD48, VPS4B_BOVIN; | O75351, VPS4B_HUMAN; |
| P46467, VPS4B_MOUSE; | Q5R658, VPS4B_PONAB; | Q54PT2, VPS4_DICDI; |
| Q09803, VPS4_SCHPO; |
|
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