ENZYME entry: EC 3.6.4.8

Accepted Name
Proteasome ATPase.
Alternative Name(s)
RP triphosphatase.
RP triple-A protein.
Reaction catalysed
ATP + H(2)O <=> ADP + phosphate
Comment(s)
  • Belongs to the AAA-type superfamily and, like EC 3.6.4.5, is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome.
  • Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome.
Cross-references
PROSITEPDOC00572
BRENDA3.6.4.8
EC2PDB3.6.4.8
ExplorEnz3.6.4.8
PRIAM enzyme-specific profiles3.6.4.8
KEGG Ligand Database for Enzyme Nomenclature3.6.4.8
IUBMB Enzyme Nomenclature3.6.4.8
IntEnz3.6.4.8
MEDLINEFind literature relating to 3.6.4.8
MetaCyc3.6.4.8

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-