ENZYME entry: EC 3.6.5.2

Accepted Name
Small monomeric GTPase.
Reaction catalysed
GTP + H(2)O <=> GDP + phosphate
Comment(s)
  • A family of about 50 enzymes with a molecular mass of 21 kDa that are distantly related to the alpha-subunit of EC 3.6.1.46.
  • Involved in cell-growth regulation (Ras subfamily), membrane vesicle traffic and uncoating (Rab and ARF subfamilies), nuclear protein import (Ran subfamily) and organization of the cytoskeleton (Rho and Rac subfamilies).
  • Formerly EC 3.6.1.47.
Cross-references
PROSITEPDOC00859
BRENDA3.6.5.2
EC2PDB3.6.5.2
ExplorEnz3.6.5.2
PRIAM enzyme-specific profiles3.6.5.2
KEGG Ligand Database for Enzyme Nomenclature3.6.5.2
IUBMB Enzyme Nomenclature3.6.5.2
IntEnz3.6.5.2
MEDLINEFind literature relating to 3.6.5.2
MetaCyc3.6.5.2

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.5.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-