ENZYME entry: EC 3.7.1.13

Accepted Name
2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase.
Reaction catalysed
(2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H(2)O <=> anthranilate + (2E)-2-hydroxypenta-2,4-dienoate
Comment(s)
  • This enzyme catalyzes the third step in the aerobic degradation pathway of carbazole.
  • The effect of the presence of an amino group or hydroxyl group at the 2-position of the substrate is small.
  • The enzyme has no cofactor requirement.
Cross-references
BRENDA3.7.1.13
EC2PDB3.7.1.13
ExplorEnz3.7.1.13
PRIAM enzyme-specific profiles3.7.1.13
KEGG Ligand Database for Enzyme Nomenclature3.7.1.13
IUBMB Enzyme Nomenclature3.7.1.13
IntEnz3.7.1.13
MEDLINEFind literature relating to 3.7.1.13
MetaCyc3.7.1.13
UniProtKB/Swiss-Prot
Q9AQM4, CARC_PSERE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-