ENZYME entry: EC 3.7.1.23

Accepted Name
Maleylpyruvate hydrolase.
Reaction catalysed
3-maleylpyruvate + H(2)O <=> maleate + pyruvate
Cofactor(s)
Mn(2+).
Comment(s)
  • The enzyme, characterized from the bacterium Pseudomonas alcaligenes NCIMB 9867, catalyzes the hydrolysis of 3-maleylpyruvate, the ring- cleavage product of gentisate.
  • The enzyme can also act on a number of maleylpyruvate derivatives, such as (2E)-2-methyl-4,6-dioxohept-2-enedioate and (2E)-3-methyl- 4,6-dioxohept-2-enedioate.
  • May be identical to EC 3.7.1.5.
Cross-references
BRENDA3.7.1.23
EC2PDB3.7.1.23
ExplorEnz3.7.1.23
PRIAM enzyme-specific profiles3.7.1.23
KEGG Ligand Database for Enzyme Nomenclature3.7.1.23
IUBMB Enzyme Nomenclature3.7.1.23
IntEnz3.7.1.23
MEDLINEFind literature relating to 3.7.1.23
MetaCyc3.7.1.23

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-