ENZYME entry: EC 3.7.1.3

Accepted Name
Kynureninase.
Alternative Name(s)
L-kynurenine hydrolase.
Reaction catalysed
L-kynurenine + H(2)O <=> anthranilate + L-alanine
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
Also acts on 3'-hydroxykynurenine and some other (3-arylcarbonyl)- alanines.
Cross-references
BRENDA3.7.1.3
EC2PDB3.7.1.3
ExplorEnz3.7.1.3
PRIAM enzyme-specific profiles3.7.1.3
KEGG Ligand Database for Enzyme Nomenclature3.7.1.3
IUBMB Enzyme Nomenclature3.7.1.3
IntEnz3.7.1.3
MEDLINEFind literature relating to 3.7.1.3
MetaCyc3.7.1.3
UniProtKB/Swiss-Prot
A1C688, KYNU1_ASPCL;  B0XS72, KYNU1_ASPFC;  Q4X1D4, KYNU1_ASPFU;  
A2R7T0, KYNU1_ASPNC;  Q2U038, KYNU1_ASPOR;  Q0CPB0, KYNU1_ASPTN;  
Q2H9P7, KYNU1_CHAGB;  Q5B0H8, KYNU1_EMENI;  A1DGW4, KYNU1_NEOFI;  
Q7S332, KYNU1_NEUCR;  Q0UIN2, KYNU1_PHANO;  A1CHT0, KYNU2_ASPCL;  
B0Y6H2, KYNU2_ASPFC;  Q4WPN0, KYNU2_ASPFU;  A2QJI5, KYNU2_ASPNC;  
Q2UJE8, KYNU2_ASPOR;  Q0CZX6, KYNU2_ASPTN;  Q2H7G2, KYNU2_CHAGB;  
Q5BC73, KYNU2_EMENI;  A1CWY1, KYNU2_NEOFI;  Q7RXY2, KYNU2_NEUCR;  
Q0UZK0, KYNU2_PHANO;  Q750P5, KYNU_ASHGO;  A0REX2, KYNU_BACAH;  
Q81PP8, KYNU_BACAN;  Q736W3, KYNU_BACC1;  A7GPY3, KYNU_BACCN;  
Q81CK0, KYNU_BACCR;  Q63AJ0, KYNU_BACCZ;  Q6HHX7, KYNU_BACHK;  
Q5WKB5, KYNU_BACSK;  A9VHP9, KYNU_BACWK;  A6RSP5, KYNU_BOTFB;  
A3MHE2, KYNU_BURM7;  A2S925, KYNU_BURM9;  Q62M98, KYNU_BURMA;  
A1V194, KYNU_BURMS;  A3NS56, KYNU_BURP0;  Q3JVD7, KYNU_BURP1;  
A3N6H3, KYNU_BURP6;  Q63WP4, KYNU_BURPS;  A8XKT0, KYNU_CAEBR;  
Q18026, KYNU_CAEEL;  Q59QC4, KYNU_CANAL;  Q1DZA6, KYNU_COCIM;  
P0CO53, KYNU_CRYNB;  P0CO52, KYNU_CRYNJ;  Q6BI19, KYNU_DEBHA;  
Q9RYH5, KYNU_DEIRA;  Q54Q04, KYNU_DICDI;  B1YHD6, KYNU_EXIS2;  
A5FMM4, KYNU_FLAJ1;  A6H1P7, KYNU_FLAPJ;  A4IT57, KYNU_GEOTN;  
A0M4Y1, KYNU_GRAFK;  Q16719, KYNU_HUMAN;  Q1ITW5, KYNU_KORVE;  
A5DTF4, KYNU_LODEL;  A4UBV5, KYNU_MAGO7;  A9V3C0, KYNU_MONBE;  
Q9CXF0, KYNU_MOUSE;  Q1DDU5, KYNU_MYXXD;  A7SCH8, KYNU_NEMVE;  
A5DM91, KYNU_PICGU;  A3LQD7, KYNU_PICST;  P83788, KYNU_PSEFL;  
P70712, KYNU_RAT;  A4XAL2, KYNU_SALTO;  Q5DGJ1, KYNU_SCHJA;  
A7ESB8, KYNU_SCLS1;  B1KJM4, KYNU_SHEWM;  B2FL97, KYNU_STRMK;  
A7TR79, KYNU_VANPO;  Q8PM33, KYNU_XANAC;  Q3BV40, KYNU_XANC5;  
Q4UT93, KYNU_XANC8;  B0RUZ9, KYNU_XANCB;  Q8PAD2, KYNU_XANCP;  
Q2P317, KYNU_XANOM;  B2SIT8, KYNU_XANOP;  Q5H039, KYNU_XANOR;  
Q6CDM0, KYNU_YARLI;  Q05979, KYNU_YEAST;  

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