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ENZYME entry: EC

Accepted Name
2-haloacid dehalogenase (configuration-inverting).
Alternative Name(s)
2-haloalkanoic acid dehalogenase.
2-haloalkanoid acid halidohydrolase.
DL-2-haloacid dehalogenase.
DL-2-haloacid dehalogenase (inversion of configuration).
DL-2-haloacid halidohydrolase (inversion of configuration).
Reaction catalysed
  • (S)-2-haloacid + H(2)O <=> (R)-2-hydroxyacid + halide
  • (R)-2-haloacid + H(2)O <=> (S)-2-hydroxyacid + halide
  • Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (R)- and (S)-hydroxyalkanoic acids, respectively, with inversion of configuration at C-2.
  • The enzyme from Pseudomonas sp. 113 acts on 2-haloalkanoic acids whose carbon chain lengths are five or less (see also EC, EC and EC
PRIAM enzyme-specific profiles3.8.1.10
KEGG Ligand Database for Enzyme Nomenclature3.8.1.10
IUBMB Enzyme Nomenclature3.8.1.10
MEDLINEFind literature relating to
O06652, HADDL_PSES4;  Q59168, HDDL_ALCXX;  

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