ENZYME entry: EC 4.1.1.3

Accepted Name
Oxaloacetate decarboxylase.
Alternative Name(s)
Oxalate beta-decarboxylase.
Oxaloacetate carboxy-lyase.
Reaction catalysed
Oxaloacetate <=> pyruvate + CO(2)
Cofactor(s)
Biotin; Mn(2+) or Na(+).
Comment(s)
  • The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.
  • The process is accompanied by the extrusion of two sodium ions from cells.
  • Some animal enzymes require manganese.
Cross-references
PROSITEPDOC00167 ; PDOC50991
BRENDA4.1.1.3
EC2PDB4.1.1.3
ExplorEnz4.1.1.3
PRIAM enzyme-specific profiles4.1.1.3
KEGG Ligand Database for Enzyme Nomenclature4.1.1.3
IUBMB Enzyme Nomenclature4.1.1.3
IntEnz4.1.1.3
MEDLINEFind literature relating to 4.1.1.3
MetaCyc4.1.1.3
UniProtKB/Swiss-Prot
P13187, DCOA_KLEPN;  Q8XGX8, DCOA_SALTI;  Q03030, DCOA_SALTY;  
Q9AQI0, HMGA_PSEOC;  A5W059, HMGA_PSEP1;  Q8Z9M6, OADB1_SALTI;  
Q8ZRY4, OADB1_SALTY;  Q8Z3E5, OADB2_SALTI;  Q03031, OADB2_SALTY;  
Q9RF98, OADB_HAEDU;  P13156, OADB_KLEPN;  Q9CL24, OADB_PASMU;  
Q9KTU5, OADB_VIBCH;  Q3KEL1, OADC1_PSEPF;  B1J195, OADC1_PSEPW;  
Q3KCJ2, OADC2_PSEPF;  B1JFP4, OADC2_PSEPW;  C1DEN4, OADC_AZOVD;  
Q89JL7, OADC_BRADU;  A5EL79, OADC_BRASB;  A4YT21, OADC_BRASO;  
Q13Q00, OADC_BURXL;  Q1R0Z3, OADC_CHRSD;  A6VZF8, OADC_MARMS;  
Q48LY6, OADC_PSE14;  A6VCY0, OADC_PSEA7;  B7V1T5, OADC_PSEA8;  
Q02FE6, OADC_PSEAB;  Q9HUU1, OADC_PSEAE;  Q1I5P3, OADC_PSEE4;  
Q4KDX1, OADC_PSEF5;  C3KBB4, OADC_PSEFS;  A4XQ41, OADC_PSEMY;  
A5W8J7, OADC_PSEP1;  B0KV77, OADC_PSEPG;  Q88N27, OADC_PSEPK;  
Q886Y2, OADC_PSESM;  Q4ZX15, OADC_PSEU2;  A4VQV5, OADC_PSEU5;  
Q2IXI7, OADC_RHOP2;  Q07L14, OADC_RHOP5;  Q6N509, OADC_RHOPA;  
Q211P3, OADC_RHOPB;  Q135C1, OADC_RHOPS;  B3QAW1, OADC_RHOPT;  
Q5PKI8, OADG1_SALPA;  Q8Z9M5, OADG1_SALTI;  P58651, OADG1_SALTY;  
Q9KUH2, OADG1_VIBCH;  Q5PJT2, OADG2_SALPA;  Q8Z3E4, OADG2_SALTI;  
Q03032, OADG2_SALTY;  Q9KTU4, OADG2_VIBCH;  P58650, OADG3_SALTY;  
A3N223, OADG_ACTP2;  B3GYF4, OADG_ACTP7;  A6VL34, OADG_ACTSZ;  
B7LVP2, OADG_ESCF3;  Q9RFA0, OADG_HAEDU;  A6T4H1, OADG_KLEP7;  
P13155, OADG_KLEPN;  Q65WL3, OADG_MANSM;  Q9CL26, OADG_PASMU;  
B5F736, OADG_SALA4;  A9MYH6, OADG_SALPB;  Q87LR6, OADG_VIBPA;  
Q8DC44, OADG_VIBVU;  Q7MHR9, OADG_VIBVY;  Q9M8R9, RRAA1_ARATH;  
Q9FFE0, RRAA2_ARATH;  Q9FH13, RRAA3_ARATH;  Q6FCF4, RRAAH_ACIAD;  
Q0VQ55, RRAAH_ALCBS;  Q0A9G6, RRAAH_ALKEH;  Q5P203, RRAAH_AROAE;  
C1DHC2, RRAAH_AZOVD;  Q81N49, RRAAH_BACAN;  Q734S7, RRAAH_BACC1;  
Q638R8, RRAAH_BACCZ;  Q9KBI9, RRAAH_BACHD;  A9AHQ6, RRAAH_BURM1;  
A3MKY3, RRAAH_BURM7;  A2SB35, RRAAH_BURM9;  Q62J86, RRAAH_BURMA;  
A1V5A8, RRAAH_BURMS;  A3NWR9, RRAAH_BURP0;  Q3JQZ3, RRAAH_BURP1;  
A3NAY8, RRAAH_BURP6;  B2JIG2, RRAAH_BURP8;  B2SXN2, RRAAH_BURPP;  
Q63SX7, RRAAH_BURPS;  Q2SX33, RRAAH_BURTA;  Q13X79, RRAAH_BURXL;  
Q7NXI6, RRAAH_CHRVO;  Q8FQY0, RRAAH_COREF;  Q8NRW6, RRAAH_CORGL;  
Q4JVU3, RRAAH_CORJK;  Q0K9J4, RRAAH_CUPNH;  Q46ZV6, RRAAH_CUPPJ;  
B3R2J3, RRAAH_CUPTR;  Q47BF5, RRAAH_DECAR;  Q9RW10, RRAAH_DEIRA;  
Q2SK70, RRAAH_HAHCH;  A1WU91, RRAAH_HALHL;  C1D7M1, RRAAH_LARHH;  
A6VX14, RRAAH_MARMS;  Q607E7, RRAAH_METCA;  A0Q981, RRAAH_MYCA1;  
P0A667, RRAAH_MYCBO;  A1KQI8, RRAAH_MYCBP;  C1AIV9, RRAAH_MYCBT;  
A4T3Z0, RRAAH_MYCGI;  B8ZTT3, RRAAH_MYCLB;  Q9CDD2, RRAAH_MYCLE;  
Q745I2, RRAAH_MYCPA;  A0R664, RRAAH_MYCS2;  A3Q7S1, RRAAH_MYCSJ;  
A1UNC5, RRAAH_MYCSK;  Q1B1S4, RRAAH_MYCSS;  A5U9I2, RRAAH_MYCTA;  
P9WGY2, RRAAH_MYCTO;  P9WGY3, RRAAH_MYCTU;  A1TGZ7, RRAAH_MYCVP;  
Q5Z3P5, RRAAH_NOCFA;  Q6LUQ3, RRAAH_PHOPR;  Q48JZ3, RRAAH_PSE14;  
A6V753, RRAAH_PSEA7;  B7VBA7, RRAAH_PSEA8;  Q02KR3, RRAAH_PSEAB;  
Q9I2W7, RRAAH_PSEAE;  Q1ICM4, RRAAH_PSEE4;  Q4KFJ3, RRAAH_PSEF5;  
Q9S4U0, RRAAH_PSEFL;  C3K0T6, RRAAH_PSEFS;  A4XU32, RRAAH_PSEMY;  
A5W6M0, RRAAH_PSEP1;  Q3KFE1, RRAAH_PSEPF;  B0KG79, RRAAH_PSEPG;  
Q88L51, RRAAH_PSEPK;  B1J596, RRAAH_PSEPW;  Q883Q6, RRAAH_PSESM;  
Q4ZUN7, RRAAH_PSEU2;  A4VL60, RRAAH_PSEU5;  Q8XZP1, RRAAH_RALSO;  
B6IPN3, RRAAH_RHOCS;  Q21X23, RRAAH_RHOFT;  A4FBN0, RRAAH_SACEN;  
Q8EE23, RRAAH_SHEON;  Q72J23, RRAAH_THET2;  Q5SIP7, RRAAH_THET8;  
B8GM40, RRAAH_THISH;  Q9KPK1, RRAAH_VIBCH;  Q87SD2, RRAAH_VIBPA;  
Q8DEP0, RRAAH_VIBVU;  Q7MNR7, RRAAH_VIBVY;  Q8PIT8, RRAAH_XANAC;  
Q3BRB4, RRAAH_XANC5;  Q4UWM5, RRAAH_XANC8;  B0RQZ0, RRAAH_XANCB;  
Q8P7H4, RRAAH_XANCP;  Q2P5H9, RRAAH_XANOM;  B2SSI8, RRAAH_XANOP;  
P40011, RRAAH_YEAST;  

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