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ENZYME entry: EC 4.1.1.37

Accepted Name
Uroporphyrinogen decarboxylase.
Alternative Name(s)
Uroporphyrinogen III decarboxylase.
Uroporphyrinogen-III carboxy-lyase.
Reaction catalysed
Uroporphyrinogen III <=> coproporphyrinogen + 4 CO(2)
Comment(s)
Acts on a number of porphyrinogens.
Cross-references
PROSITEPDOC00705
BRENDA4.1.1.37
EC2PDB4.1.1.37
ExplorEnz4.1.1.37
PRIAM enzyme-specific profiles4.1.1.37
KEGG Ligand Database for Enzyme Nomenclature4.1.1.37
IUBMB Enzyme Nomenclature4.1.1.37
IntEnz4.1.1.37
MEDLINEFind literature relating to 4.1.1.37
MetaCyc4.1.1.37
UniProtKB/Swiss-Prot
Q93ZB6, DCUP1_ARATH;  Q9AXB0, DCUP1_ORYSJ;  O22886, DCUP2_ARATH;  
Q10LR9, DCUP2_ORYSJ;  A1TVM0, DCUP_ACIAC;  Q6F9M1, DCUP_ACIAD;  
B7GZK6, DCUP_ACIB3;  B7I451, DCUP_ACIB5;  B2HVF8, DCUP_ACIBC;  
B0VUQ9, DCUP_ACIBS;  A3M795, DCUP_ACIBT;  B0VBT2, DCUP_ACIBY;  
A0LUP4, DCUP_ACIC1;  A5G1D5, DCUP_ACICJ;  B9MGH2, DCUP_ACIET;  
A1WCJ3, DCUP_ACISJ;  A3MYI4, DCUP_ACTP2;  B3GZV2, DCUP_ACTP7;  
B0BS17, DCUP_ACTPJ;  A6VQT2, DCUP_ACTSZ;  A4SJ51, DCUP_AERS4;  
Q8UBL6, DCUP_AGRT5;  Q220I2, DCUP_ALBFT;  Q0VMC3, DCUP_ALCBS;  
B6ENB7, DCUP_ALISL;  Q0A4Y2, DCUP_ALKEH;  Q2IPY2, DCUP_ANADE;  
A7H9E0, DCUP_ANADF;  Q3MC76, DCUP_ANAVT;  O66667, DCUP_AQUAE;  
A8EVQ3, DCUP_ARCB4;  Q5P4Q4, DCUP_AROAE;  A0JYN1, DCUP_ARTS2;  
A1KCN9, DCUP_AZOSB;  C1DHQ1, DCUP_AZOVD;  A7Z323, DCUP_BACA2;  
A0RAS3, DCUP_BACAH;  Q81U23, DCUP_BACAN;  B7JDM6, DCUP_BACC0;  
Q73C99, DCUP_BACC1;  B7IKE2, DCUP_BACC2;  B7HGF9, DCUP_BACC4;  
B7HZJ8, DCUP_BACC7;  A7GM02, DCUP_BACCN;  Q81GW6, DCUP_BACCR;  
Q63ES5, DCUP_BACCZ;  Q9KDL0, DCUP_BACHD;  Q6HM98, DCUP_BACHK;  
A8FBM5, DCUP_BACP2;  P32395, DCUP_BACSU;  A9VI98, DCUP_BACWK;  
Q7WEN2, DCUP_BORBR;  Q7W3B3, DCUP_BORPA;  A9HY51, DCUP_BORPD;  
Q7VU41, DCUP_BORPE;  Q89SK1, DCUP_BRADU;  A5EDY0, DCUP_BRASB;  
A4YPC0, DCUP_BRASO;  B2S965, DCUP_BRUA1;  Q2YR07, DCUP_BRUA2;  
Q57AJ2, DCUP_BRUAB;  A9M9E9, DCUP_BRUC2;  C0RFV3, DCUP_BRUMB;  
Q8YJT1, DCUP_BRUME;  A5VT24, DCUP_BRUO2;  B0CJG6, DCUP_BRUSI;  
Q8FY24, DCUP_BRUSU;  B4EEZ3, DCUP_BURCJ;  A3MQK6, DCUP_BURM7;  
A2S6J1, DCUP_BURM9;  A1V8S5, DCUP_BURMS;  A3P0Y4, DCUP_BURP0;  
A3NF35, DCUP_BURP6;  B2T7J6, DCUP_BURPP;  Q63PI5, DCUP_BURPS;  
Q2STF3, DCUP_BURTA;  A4JA40, DCUP_BURVG;  Q13SQ6, DCUP_BURXL;  
A7ZEJ7, DCUP_CAMC1;  A7GZU8, DCUP_CAMC5;  A0RQV9, DCUP_CAMFF;  
A7I2S8, DCUP_CAMHC;  A8FMU8, DCUP_CAMJ8;  A7H2D8, DCUP_CAMJD;  
Q9PN54, DCUP_CAMJE;  A1W0M7, DCUP_CAMJJ;  Q5HTL9, DCUP_CAMJR;  
B9KFM9, DCUP_CAMLR;  Q3AEU3, DCUP_CARHZ;  B8GW41, DCUP_CAUCN;  
P0CAX3, DCUP_CAUCR;  B3PDU1, DCUP_CELJU;  Q11CM8, DCUP_CHESB;  
A9WIS6, DCUP_CHLAA;  Q5L510, DCUP_CHLAB;  B8G821, DCUP_CHLAD;  
Q3AUB7, DCUP_CHLCH;  Q821R0, DCUP_CHLCV;  B3EHV5, DCUP_CHLL2;  
Q9PLH7, DCUP_CHLMU;  B3QL69, DCUP_CHLP8;  B3EL29, DCUP_CHLPB;  
A1BCW4, DCUP_CHLPD;  Q9Z716, DCUP_CHLPN;  B9LKR9, DCUP_CHLSY;  
B0B8X3, DCUP_CHLT2;  B3QXB5, DCUP_CHLT3;  Q3KKU6, DCUP_CHLTA;  
B0BAK2, DCUP_CHLTB;  Q8KAW2, DCUP_CHLTE;  O84752, DCUP_CHLTR;  
Q1R1C8, DCUP_CHRSD;  Q7NZ00, DCUP_CHRVO;  A8AKS6, DCUP_CITK8;  
Q489Q8, DCUP_COLP3;  Q6NJJ4, DCUP_CORDI;  Q8FSD6, DCUP_COREF;  
A4QB76, DCUP_CORGB;  Q8NT75, DCUP_CORGL;  B6J5G8, DCUP_COXB1;  
B6J229, DCUP_COXB2;  A9KCZ5, DCUP_COXBN;  A9NB09, DCUP_COXBR;  
Q83EP0, DCUP_COXBU;  A7MJ78, DCUP_CROS8;  Q0K5N1, DCUP_CUPNH;  
Q46VY4, DCUP_CUPPJ;  B1WVY1, DCUP_CYAA5;  B7KKW4, DCUP_CYAP7;  
Q11X05, DCUP_CYTH3;  Q9PTS2, DCUP_DANRE;  Q47K40, DCUP_DECAR;  
Q9RV96, DCUP_DEIRA;  A9BPZ7, DCUP_DELAS;  Q6ANR5, DCUP_DESPS;  
Q54DF9, DCUP_DICDI;  A5EX29, DCUP_DICNV;  A8LIJ7, DCUP_DINSH;  
Q9V595, DCUP_DROME;  O18601, DCUP_DROVI;  A7ZUL3, DCUP_ECO24;  
B7UPF2, DCUP_ECO27;  B7MIY3, DCUP_ECO45;  B7LA91, DCUP_ECO55;  
Q8X6X5, DCUP_ECO57;  B5Z093, DCUP_ECO5E;  B7NRT0, DCUP_ECO7I;  
B7N2J9, DCUP_ECO81;  B7M7Q6, DCUP_ECO8A;  C5A0T8, DCUP_ECOBW;  
B1XC00, DCUP_ECODH;  A8A797, DCUP_ECOHS;  A1AIG8, DCUP_ECOK1;  
Q0TA68, DCUP_ECOL5;  Q8FB74, DCUP_ECOL6;  B1IUQ0, DCUP_ECOLC;  
P29680, DCUP_ECOLI;  B7NFT8, DCUP_ECOLU;  B6I5K8, DCUP_ECOSE;  
B1LNU9, DCUP_ECOSM;  Q1R5W3, DCUP_ECOUT;  C5BHE8, DCUP_EDWI9;  
A4W5C0, DCUP_ENT38;  B2VG77, DCUP_ERWT9;  Q2N6J8, DCUP_ERYLH;  
B7LUK5, DCUP_ESCF3;  A5FLE7, DCUP_FLAJ1;  A6GVN8, DCUP_FLAPJ;  
B0TWR0, DCUP_FRAP2;  Q2JDD1, DCUP_FRASC;  Q14K23, DCUP_FRAT1;  
A7NEJ1, DCUP_FRATF;  Q2A1G5, DCUP_FRATH;  B2SEW4, DCUP_FRATM;  
A0Q8F6, DCUP_FRATN;  Q0BK67, DCUP_FRATO;  Q5NIM0, DCUP_FRATT;  
A4IW07, DCUP_FRATW;  B5E7R1, DCUP_GEOBB;  B9M7T4, DCUP_GEODF;  
Q5L284, DCUP_GEOKA;  B3EAR8, DCUP_GEOLS;  Q39ZQ8, DCUP_GEOMG;  
Q746R5, DCUP_GEOSL;  C6E7R9, DCUP_GEOSM;  C5D6M5, DCUP_GEOSW;  
A4IKU7, DCUP_GEOTN;  A5GDW7, DCUP_GEOUR;  Q7NEK2, DCUP_GLOVI;  
A9HDX7, DCUP_GLUDA;  Q5FS38, DCUP_GLUOX;  Q0BWA2, DCUP_GRABC;  
A0M6C4, DCUP_GRAFK;  Q2S9R0, DCUP_HAHCH;  A1WVX2, DCUP_HALHL;  
C4K8F9, DCUP_HAMD5;  Q17W45, DCUP_HELAH;  Q7VF06, DCUP_HELHP;  
B6JLI7, DCUP_HELP2;  B5Z6X6, DCUP_HELPG;  Q1CTS0, DCUP_HELPH;  
Q9ZLM8, DCUP_HELPJ;  B2UTM1, DCUP_HELPS;  O25325, DCUP_HELPY;  
A4GAF0, DCUP_HERAR;  Q0I5E2, DCUP_HISS1;  B0US07, DCUP_HISS2;  
Q42855, DCUP_HORVU;  P06132, DCUP_HUMAN;  B4U9S4, DCUP_HYDS0;  
Q0BWA4, DCUP_HYPNA;  Q5QVW3, DCUP_IDILO;  A6T450, DCUP_JANMA;  
Q28KJ9, DCUP_JANSC;  B5XYE1, DCUP_KLEP3;  A6TGQ4, DCUP_KLEP7;  
Q1ITV2, DCUP_KORVE;  Q5X3M4, DCUP_LEGPA;  A5IDL1, DCUP_LEGPC;  
Q5ZTY0, DCUP_LEGPH;  Q5WV12, DCUP_LEGPL;  Q6AHF5, DCUP_LEIXX;  
Q929G1, DCUP_LISIN;  C1KXG7, DCUP_LISMC;  Q71XF3, DCUP_LISMF;  
B8DF98, DCUP_LISMH;  Q8Y564, DCUP_LISMO;  A0AKW5, DCUP_LISW6;  
Q2VYH1, DCUP_MAGSA;  A0L3L1, DCUP_MAGSM;  O81220, DCUP_MAIZE;  
Q65W70, DCUP_MANSM;  A1TYW3, DCUP_MARAV;  Q0AKD9, DCUP_MARMM;  
Q60BY1, DCUP_METCA;  Q1GXV8, DCUP_METFK;  A2SC07, DCUP_METPP;  
B0JL12, DCUP_MICAN;  P70697, DCUP_MOUSE;  A0QIL2, DCUP_MYCA1;  
Q7TY47, DCUP_MYCBO;  A1KM16, DCUP_MYCBP;  C1AFD7, DCUP_MYCBT;  
A4TCS1, DCUP_MYCGI;  B8ZQX2, DCUP_MYCLB;  P46809, DCUP_MYCLE;  
B2HM23, DCUP_MYCMM;  Q73W61, DCUP_MYCPA;  A0QW23, DCUP_MYCS2;  
A3PYL0, DCUP_MYCSJ;  A1UF48, DCUP_MYCSK;  A5U630, DCUP_MYCTA;  
P9WFE0, DCUP_MYCTO;  P9WFE1, DCUP_MYCTU;  A0PT34, DCUP_MYCUA;  
A1T7Z4, DCUP_MYCVP;  Q1D1F0, DCUP_MYXXD;  B9L8M1, DCUP_NAUPA;  
Q5F9N1, DCUP_NEIG1;  B4RK59, DCUP_NEIG2;  A9M3L2, DCUP_NEIM0;  
Q9JV52, DCUP_NEIMA;  Q9K041, DCUP_NEIMB;  A1KT40, DCUP_NEIMF;  
Q2GCG4, DCUP_NEOSM;  Q0AIF1, DCUP_NITEC;  Q82X50, DCUP_NITEU;  
Q1QJ95, DCUP_NITHX;  Q2YB59, DCUP_NITMU;  Q3J6U6, DCUP_NITOC;  
A6Q291, DCUP_NITSB;  Q5YTA5, DCUP_NOCFA;  A1SMY9, DCUP_NOCSJ;  
B2J9R9, DCUP_NOSP7;  Q8YQC4, DCUP_NOSS1;  Q2GC56, DCUP_NOVAD;  
Q8ERY0, DCUP_OCEIH;  A6WX72, DCUP_OCHA4;  A5CDS4, DCUP_ORITB;  
B3CR66, DCUP_ORITI;  A1B852, DCUP_PARDP;  Q6MB12, DCUP_PARUW;  
P57964, DCUP_PASMU;  Q6DAL7, DCUP_PECAS;  C6DHS9, DCUP_PECCP;  
Q3A6H9, DCUP_PELCD;  Q3B1E7, DCUP_PELLD;  B4SGD6, DCUP_PELPB;  
A1ALN0, DCUP_PELPD;  B4RD11, DCUP_PHEZH;  Q7N960, DCUP_PHOLL;  
Q6LLW6, DCUP_PHOPR;  Q6KZ54, DCUP_PICTO;  A1VJ58, DCUP_POLNA;  
Q123Y6, DCUP_POLSJ;  Q5RDK5, DCUP_PONAB;  B4S3W2, DCUP_PROA2;  
A3PBV7, DCUP_PROM0;  A2C141, DCUP_PROM1;  A8G3U9, DCUP_PROM2;  
A2CAR8, DCUP_PROM3;  A9BAY8, DCUP_PROM4;  A2BVP6, DCUP_PROM5;  
Q31BV1, DCUP_PROM9;  Q7VBL3, DCUP_PROMA;  B4EYT8, DCUP_PROMH;  
Q7V8B4, DCUP_PROMM;  Q7V2A0, DCUP_PROMP;  A2BQ64, DCUP_PROMS;  
Q46LW7, DCUP_PROMT;  A4SGN6, DCUP_PROVI;  Q48PG2, DCUP_PSE14;  
Q15ZB1, DCUP_PSEA6;  A6VDF5, DCUP_PSEA7;  B7V3C7, DCUP_PSEA8;  
Q02EY3, DCUP_PSEAB;  P95458, DCUP_PSEAE;  Q1IGA3, DCUP_PSEE4;  
Q4KJI4, DCUP_PSEF5;  C3KBH3, DCUP_PSEFS;  Q3IJU2, DCUP_PSEHT;  
A4XPQ6, DCUP_PSEMY;  A5WAA7, DCUP_PSEP1;  Q3KJ97, DCUP_PSEPF;  
B0KN28, DCUP_PSEPG;  Q88CV6, DCUP_PSEPK;  B1J2J9, DCUP_PSEPW;  
Q87V23, DCUP_PSESM;  Q4ZZD8, DCUP_PSEU2;  Q4FRK8, DCUP_PSYA2;  
Q1QA45, DCUP_PSYCK;  A1SZJ4, DCUP_PSYIN;  A5WFU9, DCUP_PSYWF;  
Q1LHL3, DCUP_RALME;  B2UGT5, DCUP_RALPJ;  Q8XU90, DCUP_RALSO;  
P32362, DCUP_RAT;  Q1MA15, DCUP_RHIL3;  Q98DY6, DCUP_RHILO;  
C3MB70, DCUP_RHISN;  P42503, DCUP_RHOCA;  C0ZYX0, DCUP_RHOE4;  
C1B4A1, DCUP_RHOOB;  Q2ISV3, DCUP_RHOP2;  Q07S20, DCUP_RHOP5;  
Q132J9, DCUP_RHOPS;  Q2RN85, DCUP_RHORT;  A3PM71, DCUP_RHOS1;  
P32920, DCUP_RHOS4;  A4WPZ2, DCUP_RHOS5;  B9KLM3, DCUP_RHOSK;  
Q0S1F6, DCUP_RHOSR;  C3PM28, DCUP_RICAE;  A8GQC1, DCUP_RICAH;  
A8GYD8, DCUP_RICB8;  Q1RGK4, DCUP_RICBR;  A8F0B3, DCUP_RICCK;  
Q92FV3, DCUP_RICCN;  Q4UJN8, DCUP_RICFE;  A8F331, DCUP_RICM5;  
Q9ZC83, DCUP_RICPR;  C4K2Z1, DCUP_RICPU;  B0BVQ6, DCUP_RICRO;  
A8GU66, DCUP_RICRS;  Q68VM8, DCUP_RICTY;  A7NKU6, DCUP_ROSCS;  
Q16AR3, DCUP_ROSDO;  A5UU35, DCUP_ROSS1;  Q5LMB5, DCUP_RUEPO;  
Q1GDK6, DCUP_RUEST;  A1AXS4, DCUP_RUTMC;  Q21H88, DCUP_SACD2;  
A4FAS3, DCUP_SACEN;  B5F1I0, DCUP_SALA4;  A9MHD2, DCUP_SALAR;  
Q57H58, DCUP_SALCH;  B5FQL2, DCUP_SALDC;  B5QYF2, DCUP_SALEP;  
B5RFI7, DCUP_SALG2;  B4TCT6, DCUP_SALHS;  B4T0Z9, DCUP_SALNS;  
Q5PKA3, DCUP_SALPA;  A9N0K9, DCUP_SALPB;  C0Q2S9, DCUP_SALPC;  
B5BJR6, DCUP_SALPK;  Q2S1W0, DCUP_SALRD;  B4TQK7, DCUP_SALSV;  
Q8Z329, DCUP_SALTI;  A4X548, DCUP_SALTO;  Q9L9I4, DCUP_SALTY;  
Q9USJ5, DCUP_SCHPO;  A8G8F7, DCUP_SERP5;  A1S2J2, DCUP_SHEAM;  
B8E642, DCUP_SHEB2;  A3CZN2, DCUP_SHEB5;  A6WTA5, DCUP_SHEB8;  
A9L5A8, DCUP_SHEB9;  Q12S16, DCUP_SHEDO;  Q8HY31, DCUP_SHEEP;  
Q088H1, DCUP_SHEFN;  B0TR87, DCUP_SHEHH;  A3QIJ0, DCUP_SHELP;  
Q8EJM8, DCUP_SHEON;  A8GZL8, DCUP_SHEPA;  A4YAY4, DCUP_SHEPC;  
B8CTX5, DCUP_SHEPW;  A0KSA9, DCUP_SHESA;  A8FQD0, DCUP_SHESH;  
Q0HN48, DCUP_SHESM;  Q0HQN5, DCUP_SHESR;  A1RFE3, DCUP_SHESW;  
B1KN91, DCUP_SHEWM;  B2TWI4, DCUP_SHIB3;  Q31U00, DCUP_SHIBS;  
Q32AH0, DCUP_SHIDS;  Q0SY03, DCUP_SHIF8;  Q83PB7, DCUP_SHIFL;  
Q3YUY7, DCUP_SHISS;  A6UEF2, DCUP_SINMW;  Q2NWR2, DCUP_SODGM;  
Q01W10, DCUP_SOLUE;  A9FZW7, DCUP_SORC5;  Q1GP74, DCUP_SPHAL;  
A5VA70, DCUP_SPHWW;  A7X3T8, DCUP_STAA1;  A6U2T7, DCUP_STAA2;  
Q2FFR2, DCUP_STAA3;  Q2FXA3, DCUP_STAA8;  A5ITZ9, DCUP_STAA9;  
Q2YU05, DCUP_STAAB;  Q5HEU2, DCUP_STAAC;  A6QI15, DCUP_STAAE;  
P67419, DCUP_STAAM;  P67420, DCUP_STAAN;  Q6GFM3, DCUP_STAAR;  
Q6G8A2, DCUP_STAAS;  A8YY02, DCUP_STAAT;  P67421, DCUP_STAAW;  
B9DN00, DCUP_STACT;  Q5HNA4, DCUP_STAEQ;  Q8CNS0, DCUP_STAES;  
Q4L7D8, DCUP_STAHJ;  Q49YM7, DCUP_STAS1;  Q82KY4, DCUP_STRAW;  
O69861, DCUP_STRCO;  B1VWH6, DCUP_STRGG;  Q30SW8, DCUP_SULDN;  
A6QAQ4, DCUP_SULNB;  P16891, DCUP_SYNE7;  Q2JX97, DCUP_SYNJA;  
Q2JKH3, DCUP_SYNJB;  B1XIF6, DCUP_SYNP2;  Q5N4W6, DCUP_SYNP6;  
A5GJR6, DCUP_SYNPW;  Q7U645, DCUP_SYNPX;  A5GSG3, DCUP_SYNR3;  
Q0I8Y1, DCUP_SYNS3;  Q3AYE3, DCUP_SYNS9;  Q3AKV7, DCUP_SYNSC;  
P54224, DCUP_SYNY3;  C5BRJ3, DCUP_TERTT;  Q9HLB9, DCUP_THEAC;  
Q8DKW0, DCUP_THEEB;  Q47NN7, DCUP_THEFY;  Q72L31, DCUP_THET2;  
Q5SKP2, DCUP_THET8;  B5YK82, DCUP_THEYD;  Q31JF4, DCUP_THICR;  
B8GPU3, DCUP_THISH;  Q42967, DCUP_TOBAC;  C4LAY4, DCUP_TOLAT;  
Q114U6, DCUP_TRIEI;  Q83H92, DCUP_TROW8;  Q83FJ0, DCUP_TROWT;  
C5CLI6, DCUP_VARPS;  A1WDU6, DCUP_VEREI;  A5CVK5, DCUP_VESOH;  
A5F3N0, DCUP_VIBC3;  A7N075, DCUP_VIBCB;  Q9KV26, DCUP_VIBCH;  
Q5E249, DCUP_VIBF1;  B5FC78, DCUP_VIBFM;  Q87KR0, DCUP_VIBPA;  
Q8DD14, DCUP_VIBVU;  Q7MGS7, DCUP_VIBVY;  Q8CWI5, DCUP_WIGBR;  
Q73GC9, DCUP_WOLPM;  B3CM33, DCUP_WOLPP;  Q7MAA5, DCUP_WOLSU;  
Q5GTT1, DCUP_WOLTR;  C0R449, DCUP_WOLWR;  Q8PI85, DCUP_XANAC;  
Q3BQR9, DCUP_XANC5;  Q4UX89, DCUP_XANC8;  B0RQC7, DCUP_XANCB;  
Q8P6X1, DCUP_XANCP;  Q2P6D1, DCUP_XANOM;  B2SKP7, DCUP_XANOP;  
Q5H3H5, DCUP_XANOR;  B2I9F9, DCUP_XYLF2;  Q9PDP7, DCUP_XYLFA;  
B0U6C5, DCUP_XYLFM;  Q87DV0, DCUP_XYLFT;  P32347, DCUP_YEAST;  
A1JIJ1, DCUP_YERE8;  A7FNH2, DCUP_YERP3;  Q1C1V3, DCUP_YERPA;  
B2K124, DCUP_YERPB;  Q8ZAQ7, DCUP_YERPE;  A9R8D5, DCUP_YERPG;  
Q1CN66, DCUP_YERPN;  A4TS20, DCUP_YERPP;  Q66FP1, DCUP_YERPS;  
B1JJL0, DCUP_YERPY;  

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