ENZYME entry: EC 4.1.1.70

Accepted Name
Glutaconyl-CoA decarboxylase.
Alternative Name(s)
4-carboxybut-2-enoyl-CoA carboxy-lyase.
Glutaconyl coenzyme A decarboxylase.
Pent-2-enoyl-CoA carboxy-lyase.
Reaction catalysed
4-carboxybut-2-enoyl-CoA <=> but-2-enoyl-CoA + CO(2)
Cofactor(s)
Biotin.
Comment(s)
  • The enzyme from Acidaminococcus fermentans is a biotinyl-protein, requires sodium, and acts as a sodium pump.
  • Prior to the sodium dependent decarboxylation, the carboxylate is transferred to biotin in a sodium independent manner.
Cross-references
PROSITEPDOC00167 ; PDOC50980
BRENDA4.1.1.70
EC2PDB4.1.1.70
ExplorEnz4.1.1.70
PRIAM enzyme-specific profiles4.1.1.70
KEGG Ligand Database for Enzyme Nomenclature4.1.1.70
IUBMB Enzyme Nomenclature4.1.1.70
IntEnz4.1.1.70
MEDLINEFind literature relating to 4.1.1.70
MetaCyc4.1.1.70
UniProtKB/Swiss-Prot
Q06700, GCDA_ACIFV;  Q9ZAA6, GCDB_ACIFV;  Q9ZAA7, GCDC_ACIFV;  
Q9ZAA8, GCDD_ACIFV;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-