ENZYME entry: EC 4.1.1.98

Accepted Name
4-hydroxy-3-polyprenylbenzoate decarboxylase.
Alternative Name(s)
3-octaprenyl-4-hydroxybenzoate decarboxylase.
4-hydroxy-3-solanesylbenzoate decarboxylase.
Reaction catalysed
A 4-hydroxy-3-polyprenylbenzoate <=> a 2-polyprenylphenol + CO(2)
Comment(s)
  • The enzyme catalyzes a step in prokaryotic ubiquinone biosynthesis, as well as in plastoquinone biosynthesis in cyanobacteria.
  • The enzyme can accept substrates with different polyprenyl tail lengths in vitro, but uses a specific length in vivo, which is determined by the polyprenyl diphosphate synthase that exists in the specific organism.
  • It requires a prenylated flavin cofactor that is produced by EC 2.5.1.129.
Cross-references
BRENDA4.1.1.98
EC2PDB4.1.1.98
ExplorEnz4.1.1.98
PRIAM enzyme-specific profiles4.1.1.98
KEGG Ligand Database for Enzyme Nomenclature4.1.1.98
IUBMB Enzyme Nomenclature4.1.1.98
IntEnz4.1.1.98
MEDLINEFind literature relating to 4.1.1.98
MetaCyc4.1.1.98
UniProtKB/Swiss-Prot
A3N287, UBID_ACTP2;  B3H2C0, UBID_ACTP7;  B0BR38, UBID_ACTPJ;  
A0KEH3, UBID_AERHH;  A4STJ3, UBID_AERS4;  Q0VLN5, UBID_ALCBS;  
Q0A5L6, UBID_ALKEH;  B4RY55, UBID_ALTMD;  Q5P5M6, UBID_AROAE;  
A1KBR8, UBID_AZOSB;  C1DJ26, UBID_AZOVD;  Q7VRJ3, UBID_BLOFL;  
Q491V9, UBID_BLOPB;  Q7WML9, UBID_BORBR;  Q7WB52, UBID_BORPA;  
A9HZS2, UBID_BORPD;  Q7VZ72, UBID_BORPE;  Q1BYC0, UBID_BURCA;  
Q39IR6, UBID_BURL3;  A9AF28, UBID_BURM1;  Q62HU9, UBID_BURMA;  
Q3JPM4, UBID_BURP1;  B2T6D4, UBID_BURPP;  Q63RP1, UBID_BURPS;  
Q2SYC8, UBID_BURTA;  Q13V32, UBID_BURXL;  B3PI23, UBID_CELJU;  
Q1R011, UBID_CHRSD;  Q7NQN3, UBID_CHRVO;  A8ACZ0, UBID_CITK8;  
Q48AG8, UBID_COLP3;  A7MQM8, UBID_CROS8;  Q1LJV5, UBID_CUPMC;  
Q474N8, UBID_CUPPJ;  B3R5V3, UBID_CUPTR;  Q47J09, UBID_DECAR;  
A7ZU48, UBID_ECO24;  P58194, UBID_ECO57;  A8A6U8, UBID_ECOHS;  
A1AI30, UBID_ECOK1;  Q0TAL3, UBID_ECOL5;  P0AAB5, UBID_ECOL6;  
B1IW64, UBID_ECOLC;  P0AAB4, UBID_ECOLI;  Q1R469, UBID_ECOUT;  
C5BCB4, UBID_EDWI9;  A4WFX7, UBID_ENT38;  B2VFE2, UBID_ERWT9;  
Q9RPX1, UBID_HAEDU;  B8F7S2, UBID_HAEPS;  Q0I278, UBID_HAES1;  
Q2SQ75, UBID_HAHCH;  A1WZD4, UBID_HALHL;  C4K7Y1, UBID_HAMD5;  
A4G3Y4, UBID_HERAR;  B0USL2, UBID_HISS2;  Q5QYG1, UBID_IDILO;  
A6T0H8, UBID_JANMA;  B5XYH3, UBID_KLEP3;  A6TGM1, UBID_KLEP7;  
C1DCP3, UBID_LARHH;  Q5X0U5, UBID_LEGPA;  A5IIC6, UBID_LEGPC;  
Q5ZRE9, UBID_LEGPH;  Q5WSL6, UBID_LEGPL;  A1TXW4, UBID_MARHV;  
Q602K0, UBID_METCA;  Q5F742, UBID_NEIG1;  B4RN63, UBID_NEIG2;  
Q9JT68, UBID_NEIMA;  Q9JY86, UBID_NEIMB;  A1KVA2, UBID_NEIMF;  
Q0AH00, UBID_NITEC;  Q82TP1, UBID_NITEU;  Q2Y5S4, UBID_NITMU;  
Q3JEK5, UBID_NITOC;  Q9CP43, UBID_PASMU;  Q6DAP8, UBID_PECAS;  
Q7MZ89, UBID_PHOLL;  B4EWD9, UBID_PROMH;  Q48PS5, UBID_PSE14;  
A6VE11, UBID_PSEA7;  B7V5C7, UBID_PSEA8;  Q02EC7, UBID_PSEAB;  
Q9HTV3, UBID_PSEAE;  Q1I337, UBID_PSEE4;  Q4K3Z5, UBID_PSEF5;  
C3K3Y8, UBID_PSEFS;  Q3IDJ8, UBID_PSEHT;  A4XP18, UBID_PSEMY;  
A5WAT0, UBID_PSEP1;  Q3K4W3, UBID_PSEPF;  B0KP99, UBID_PSEPG;  
Q88CG8, UBID_PSEPK;  B1JFC8, UBID_PSEPW;  Q87UQ5, UBID_PSESM;  
Q4ZZP7, UBID_PSEU2;  A4VGZ9, UBID_PSEU5;  A1SZG1, UBID_PSYIN;  
B2U7E6, UBID_RALPJ;  Q8Y1I2, UBID_RALSO;  Q223B1, UBID_RHOFT;  
Q21EG7, UBID_SACD2;  A9MIX5, UBID_SALAR;  Q57HN0, UBID_SALCH;  
Q5PKQ5, UBID_SALPA;  A9MYA6, UBID_SALPB;  Q8Z3C3, UBID_SALTI;  
Q9L6M0, UBID_SALTY;  A1S2N0, UBID_SHEAM;  B8E5Z9, UBID_SHEB2;  
A3CZT2, UBID_SHEB5;  A6WT44, UBID_SHEB8;  A9L4M9, UBID_SHEB9;  
Q12JN9, UBID_SHEDO;  Q07XN9, UBID_SHEFN;  B0TS25, UBID_SHEHH;  
A3Q9T4, UBID_SHELP;  Q8EJG1, UBID_SHEON;  A8GZW2, UBID_SHEPA;  
A4YAT1, UBID_SHEPC;  B8CTN5, UBID_SHEPW;  A0KSH7, UBID_SHESA;  
A8FQJ5, UBID_SHESH;  Q0HMY1, UBID_SHESM;  Q0HQV0, UBID_SHESR;  
A1RFJ5, UBID_SHESW;  B1KK65, UBID_SHEWM;  Q31UE5, UBID_SHIBS;  
Q32A18, UBID_SHIDS;  Q0SZ33, UBID_SHIF8;  Q83PG4, UBID_SHIFL;  
Q3YVC4, UBID_SHISS;  Q2NWT4, UBID_SODGM;  Q3SMI8, UBID_THIDA;  
B8GSS8, UBID_THISH;  C4LD33, UBID_TOLAT;  Q8D380, UBID_WIGBR;  
A1JIG1, UBID_YERE8;  A7FDE9, UBID_YERP3;  Q1C2C1, UBID_YERPA;  
Q0WAP0, UBID_YERPE;  A9R751, UBID_YERPG;  Q1CNA2, UBID_YERPN;  
Q66FS1, UBID_YERPS;  

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