ID   4.1.2.13
DE   Fructose-bisphosphate aldolase.
AN   Aldolase.
AN   D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase.
AN   Fructose-1,6-bisphosphate triosephosphate-lyase.
CA   D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde
CA   3-phosphate.
CF   Zinc.
CC   -!- Also acts on (3S,4R)-ketose 1-phosphates.
CC   -!- The enzymes increase electron-attraction by the carbonyl group, some
CC       (Class I) forming a protonated imine with it, others (Class II),
CC       mainly of microbial origin, polarizing it with a metal ion, e.g.
CC       zinc.
CC   -!- Formerly EC 4.1.2.7.
PR   PROSITE; PDOC00143;
PR   PROSITE; PDOC00523;
DR   Q4KMC8, ALDCA_DANRE;  Q8JH70, ALDCB_DANRE;  P04075, ALDOA_HUMAN;
DR   P05064, ALDOA_MOUSE;  A5A6I5, ALDOA_PANTR;  Q5NVR5, ALDOA_PONAB;
DR   P00883, ALDOA_RABIT;  P05065, ALDOA_RAT  ;  Q3T0S5, ALDOB_BOVIN;
DR   P07341, ALDOB_CHICK;  Q8JH71, ALDOB_DANRE;  P05062, ALDOB_HUMAN;
DR   Q91Y97, ALDOB_MOUSE;  Q5RFA6, ALDOB_PONAB;  P79226, ALDOB_RABIT;
DR   P00884, ALDOB_RAT  ;  P52210, ALDOB_SHEEP;  P53447, ALDOB_SPAAU;
DR   P53448, ALDOC_CARAU;  P53449, ALDOC_CHICK;  P09972, ALDOC_HUMAN;
DR   Q9GKW3, ALDOC_MACFA;  P05063, ALDOC_MOUSE;  Q5R1X4, ALDOC_PANTR;
DR   P09117, ALDOC_RAT  ;  Q9YG90, ALF1_AERPE ;  P54216, ALF1_CAEEL ;
DR   Q9PKH8, ALF1_CHLMU ;  Q9Z8Q7, ALF1_CHLPN ;  O84217, ALF1_CHLTR ;
DR   Q97TN4, ALF1_CLOAB ;  A6LXU8, ALF1_CLOB8 ;  Q59100, ALF1_CUPNH ;
DR   P0A992, ALF1_ECOL6 ;  P0A991, ALF1_ECOLI ;  Q8RGH3, ALF1_FUSNN ;
DR   P53445, ALF1_LAMJA ;  Q8ELI2, ALF1_OCEIH ;  Q96UH7, ALF1_PARBA ;
DR   P46256, ALF1_PEA   ;  B2RLG9, ALF1_PORG3 ;  P60053, ALF1_PORGI ;
DR   Q9V2I6, ALF1_PYRAB ;  P58314, ALF1_PYRFU ;  O57840, ALF1_PYRHO ;
DR   Q8J308, ALF1_PYRKO ;  P27995, ALF1_RHOSH ;  A7X6Y6, ALF1_STAA1 ;
DR   A6U4Y6, ALF1_STAA2 ;  Q2FDQ4, ALF1_STAA3 ;  Q2FV17, ALF1_STAA8 ;
DR   A5IW31, ALF1_STAA9 ;  Q2YWF3, ALF1_STAAB ;  Q5HCU6, ALF1_STAAC ;
DR   A6QK93, ALF1_STAAE ;  P67472, ALF1_STAAM ;  P99117, ALF1_STAAN ;
DR   Q6GDJ7, ALF1_STAAR ;  Q6G670, ALF1_STAAS ;  A8Z3K5, ALF1_STAAT ;
DR   Q8NUM5, ALF1_STAAW ;  Q07159, ALF1_STACT ;  Q5HL21, ALF1_STAEQ ;
DR   Q8CMY5, ALF1_STAES ;  Q4L9B6, ALF1_STAHJ ;  P74309, ALF1_SYNY3 ;
DR   P58315, ALF1_THETK ;  Q73QV3, ALF1_TREDE ;  Q8PHB5, ALF1_XANAC ;
DR   Q8P5Z7, ALF1_XANCP ;  Q9PF52, ALF1_XYLFA ;  Q87AI0, ALF1_XYLFT ;
DR   P46563, ALF2_CAEEL ;  Q59101, ALF2_CUPNH ;  P53446, ALF2_LAMJA ;
DR   Q8J0N6, ALF2_PARBA ;  P46257, ALF2_PEA   ;  P49577, ALF2_PLABA ;
DR   P50923, ALF2_RHOCA ;  P29271, ALF2_RHOSH ;  Q5HE75, ALF2_STAAC ;
DR   P67477, ALF2_STAAM ;  P99075, ALF2_STAAN ;  Q6GEV0, ALF2_STAAR ;
DR   Q6G7I5, ALF2_STAAS ;  P67478, ALF2_STAAW ;  Q5HM97, ALF2_STAEQ ;
DR   Q8CNI3, ALF2_STAES ;  Q55664, ALF2_SYNY3 ;  Q9SJU4, ALFC1_ARATH;
DR   Q01516, ALFC1_PEA  ;  Q944G9, ALFC2_ARATH;  Q01517, ALFC2_PEA  ;
DR   Q9ZU52, ALFC3_ARATH;  Q42690, ALFC_CHLRE ;  Q40677, ALFC_ORYSJ ;
DR   P84722, ALFC_PINST ;  P16096, ALFC_SPIOL ;  P83155, ALF_ANASL  ;
DR   P22197, ALF_ARATH  ;  Q9HGY9, ALF_ASPOR  ;  P13243, ALF_BACSU  ;
DR   O51401, ALF_BORBU  ;  P57526, ALF_BUCAI  ;  Q8K9B2, ALF_BUCAP  ;
DR   Q89AB6, ALF_BUCBP  ;  Q0PAS0, ALF_CAMJE  ;  A1VYV7, ALF_CAMJJ  ;
DR   Q9URB4, ALF_CANAL  ;  O65735, ALF_CICAR  ;  P0CJ44, ALF_COCIM  ;
DR   P19537, ALF_CORGL  ;  Q86A67, ALF_DICDI  ;  P07764, ALF_DROME  ;
DR   Q9GP32, ALF_ECHMU  ;  P0AB72, ALF_ECO57  ;  P0AB71, ALF_ECOLI  ;
DR   O52402, ALF_EDWI9  ;  Q8SSM8, ALF_ENCCU  ;  P94453, ALF_GEOSE  ;
DR   P44429, ALF_HAEIN  ;  Q9ZMQ6, ALF_HELPJ  ;  P56109, ALF_HELPY  ;
DR   Q9C2U0, ALF_KLULA  ;  P91759, ALF_LYMST  ;  P08440, ALF_MAIZE  ;
DR   P67476, ALF_MYCBO  ;  P47269, ALF_MYCGE  ;  O69600, ALF_MYCLE  ;
DR   P75089, ALF_MYCPN  ;  P67475, ALF_MYCTU  ;  P53444, ALF_NEUCR  ;
DR   Q9XDP3, ALF_NOSCO  ;  Q8YNK2, ALF_NOSS1  ;  P17784, ALF_ORYSJ  ;
DR   Q7KQL9, ALF_PLAF7  ;  P14223, ALF_PLAFA  ;  Q9I5Y1, ALF_PSEAE  ;
DR   O87796, ALF_PSEST  ;  P58336, ALF_RHIME  ;  P53442, ALF_SCHMA  ;
DR   P36580, ALF_SCHPO  ;  P0AB73, ALF_SHIFL  ;  P56888, ALF_SINMW  ;
DR   P29356, ALF_SPIOL  ;  Q9X8R6, ALF_STRCO  ;  Q9ZEM7, ALF_STRGB  ;
DR   P68905, ALF_STRP1  ;  P0CZ58, ALF_STRP3  ;  Q5XA12, ALF_STRP6  ;
DR   P68906, ALF_STRP8  ;  P0A4S1, ALF_STRPN  ;  P0CZ59, ALF_STRPQ  ;
DR   P0A4S2, ALF_STRR6  ;  Q703I2, ALF_THECA  ;  O83668, ALF_TREPA  ;
DR   P07752, ALF_TRYBB  ;  Q9PPP3, ALF_UREPA  ;  Q56815, ALF_XANFL  ;
DR   P14540, ALF_YEAST  ;  Q58980, DKFP_METJA ;
//