ID   4.1.2.25
DE   dihydroneopterin aldolase.
AN   2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-
AN   dihydropteridine glycolaldehyde-lyase.
AN   7,8-dihydroneopterin aldolase.
CA   7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin +
CA   glycolaldehyde.
CC   -!- The enzyme participates in folate (in bacteria, plants and fungi) and
CC       methanopterin (in archaea) biosynthesis.
CC   -!- The enzymes from the bacterium Escherichia coli and the plant
CC       Arabidopsis thaliana also catalyze the epimerisation of the 2'
CC       hydroxy-group (EC 5.1.99.8).
CC   -!- The enzyme from the bacterium Mycobacterium tuberculosis is
CC       trifunctional and also catalyzes EC 5.1.99.8 and EC 1.13.11.81.
CC   -!- The enzyme from the yeast Saccharomyces cerevisiae also catalyzes the
CC       two subsequent steps in the folate biosynthesis pathway - EC 2.7.6.3
CC       and EC 2.5.1.15.
DR   Q54YD9, FOL1_DICDI ;  P29251, FOL1_PNECA ;  Q4LB35, FOL1_SCHPO ;
DR   P53848, FOL1_YEAST ;  Q9SF23, FOLB1_ARATH;  Q9FM54, FOLB2_ARATH;
DR   Q6GKX5, FOLB3_ARATH;  P28823, FOLB_BACSU ;  Q9PJC6, FOLB_CHLMU ;
DR   Q9Z7E9, FOLB_CHLPN ;  O84620, FOLB_CHLTR ;  P0AC17, FOLB_ECOL6 ;
DR   P0AC16, FOLB_ECOLI ;  P46362, FOLB_HAEIN ;  P71513, FOLB_METEA ;
DR   P0A581, FOLB_MYCBO ;  O69529, FOLB_MYCLE ;  P9WNC4, FOLB_MYCTO ;
DR   P9WNC5, FOLB_MYCTU ;  P0AC18, FOLB_SHIFL ;  Q5HIG0, FOLB_STAAC ;
DR   P64145, FOLB_STAAM ;  P64146, FOLB_STAAN ;  Q6GJF6, FOLB_STAAR ;
DR   Q6GBX3, FOLB_STAAS ;  P56740, FOLB_STAAU ;  P64147, FOLB_STAAW ;
DR   Q5HRN9, FOLB_STAEQ ;  Q8CMT8, FOLB_STAES ;  Q59920, FOLB_STAHA ;
DR   Q9X8I0, FOLB_STRCO ;  P0C0G5, FOLB_STRP1 ;  P0DB12, FOLB_STRP3 ;
DR   Q5XCA7, FOLB_STRP6 ;  P0A3E2, FOLB_STRP8 ;  P0DB13, FOLB_STRPQ ;
DR   P0C0G4, FOLB_STRPY ;  P74342, FOLB_SYNY3 ;  Q57851, MPTD_METJA ;
DR   Q8TX89, MPTD_METKA ;  Q6L2J9, MPTD_PICTO ;  P22291, SULD_STRPN ;
DR   P59657, SULD_STRR6 ;
//