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ENZYME

ENZYME entry: EC 4.1.2.48

Accepted Name
low-specificity L-threonine aldolase
Reaction catalysed
  • L-threonine <=> acetaldehyde + glycine
  • L-allo-threonine <=> acetaldehyde + glycine
Comment(s)
  • The low-specificity L-threonine aldolase can act on both L-threonine and L-allo-threonine.
  • The enzyme from Escherichia coli can also act on L-threo-phenylserine and L-erythro-phenylserine.
  • The enzyme can also catalyze the aldol condensation of glycolaldehyde and glycine to form 4-hydroxy-L-threonine, an intermediate of pyridoxal phosphate biosynthesis.
  • Different from EC 4.1.2.5 and EC 4.1.2.49.
Cross-references
BRENDA4.1.2.48
EC2PDB4.1.2.48
ExplorEnz4.1.2.48
PRIAM enzyme-specific profiles4.1.2.48
KEGG Ligand Database for Enzyme Nomenclature4.1.2.48
IUBMB Enzyme Nomenclature4.1.2.48
IntEnz4.1.2.48
MEDLINEFind literature relating to 4.1.2.48
MetaCyc4.1.2.48
Rhea expert-curated reactions4.1.2.48
UniProtKB/Swiss-Prot
O13427, GLY1_CANAXO74267, GLY1_EREGSO13940, GLY1_SCHPO
P37303, GLY1_YEASTD3DKC4, GLYA_HYDTTP58319, LTAE_ECO57
P75823, LTAE_ECOLIQ9HTF1, LTAE_PSEAEO50584, LTAE_PSEUN
Q8RXU4, THA1_ARATHQ9FPH3, THA2_ARATH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-