ENZYME entry: EC 4.1.3.25

Accepted Name
(S)-citramalyl-CoA lyase.
Alternative Name(s)
(3S)-citramalyl-CoA pyruvate-lyase.
Citramalyl-CoA lyase.
Reaction catalysed
(3S)-citramalyl-CoA <=> acetyl-CoA + pyruvate
Cofactor(s)
Magnesium.
Comment(s)
  • The enzyme from the bacterium Clostridium tetanomorphum is a component of EC 4.1.3.22.
  • It also acts on (3S)-citramalyl thioacyl-carrier protein.
  • The enzyme from the bacterium Chloroflexus aurantiacus also has the activity of EC 4.1.3.24.
  • It has no activity with (3R)-citramalyl-CoA (cf. EC 4.1.3.46).
Cross-references
BRENDA4.1.3.25
EC2PDB4.1.3.25
ExplorEnz4.1.3.25
PRIAM enzyme-specific profiles4.1.3.25
KEGG Ligand Database for Enzyme Nomenclature4.1.3.25
IUBMB Enzyme Nomenclature4.1.3.25
IntEnz4.1.3.25
MEDLINEFind literature relating to 4.1.3.25
MetaCyc4.1.3.25
UniProtKB/Swiss-Prot
A9WC35, MCLA_CHLAA;  S5N020, MCLA_CHLAU;  

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