ENZYME entry: EC 4.1.3.3

Accepted Name
N-acetylneuraminate lyase.
Alternative Name(s)
N-acetylneuraminate pyruvate-lyase.
N-acetylneuraminic acid aldolase.
Reaction catalysed
N-acetylneuraminate <=> N-acetyl-D-mannosamine + pyruvate
Comment(s)
Also acts on N-glycoloylneuraminate, and on O-acetylated sialic acids, other than 4-O-acetylated derivatives.
Cross-references
PROSITEPDOC00569
BRENDA4.1.3.3
EC2PDB4.1.3.3
ExplorEnz4.1.3.3
PRIAM enzyme-specific profiles4.1.3.3
KEGG Ligand Database for Enzyme Nomenclature4.1.3.3
IUBMB Enzyme Nomenclature4.1.3.3
IntEnz4.1.3.3
MEDLINEFind literature relating to 4.1.3.3
MetaCyc4.1.3.3
UniProtKB/Swiss-Prot
Q8FD58, NANA1_ECOL6;  Q8FDU7, NANA2_ECOL6;  A3N352, NANA_ACTP2;  
B3GZ05, NANA_ACTP7;  B0BSI2, NANA_ACTPJ;  A8AQB6, NANA_CITK8;  
Q0TUP8, NANA_CLOP1;  Q9S4K9, NANA_CLOPE;  Q0SWI8, NANA_CLOPS;  
A7ZSB8, NANA_ECO24;  B7UJV8, NANA_ECO27;  B7MBY7, NANA_ECO45;  
B7LHT3, NANA_ECO55;  P0A6L5, NANA_ECO57;  B5YSV2, NANA_ECO5E;  
B7NKT6, NANA_ECO7I;  B7M0T7, NANA_ECO8A;  C4ZSW3, NANA_ECOBW;  
B1XHJ8, NANA_ECODH;  A8A535, NANA_ECOHS;  A1AGB9, NANA_ECOK1;  
Q0TCP1, NANA_ECOL5;  B1IQQ4, NANA_ECOLC;  P0A6L4, NANA_ECOLI;  
B6I1U3, NANA_ECOSE;  B1LGJ0, NANA_ECOSM;  Q1R6B5, NANA_ECOUT;  
A4WF38, NANA_ENT38;  B7LRJ3, NANA_ESCF3;  Q8RDN6, NANA_FUSNN;  
P44539, NANA_HAEIN;  Q0I2T8, NANA_HAES1;  B0UTI7, NANA_HISS2;  
P59407, NANA_LACPL;  Q9CKB0, NANA_PASMU;  Q92WP0, NANA_RHIME;  
B5F7J9, NANA_SALA4;  A9MNY6, NANA_SALAR;  Q57JC9, NANA_SALCH;  
B5FIR8, NANA_SALDC;  B5R0L2, NANA_SALEP;  B5RET7, NANA_SALG2;  
B4TJR3, NANA_SALHS;  B4T750, NANA_SALNS;  Q5PLE9, NANA_SALPA;  
A9N833, NANA_SALPB;  C0PZN4, NANA_SALPC;  B5BGP5, NANA_SALPK;  
B4TWJ0, NANA_SALSV;  Q8Z3F0, NANA_SALTI;  Q8ZLQ6, NANA_SALTY;  
B2U1V9, NANA_SHIB3;  Q31W94, NANA_SHIBS;  Q32BB4, NANA_SHIDS;  
Q0T065, NANA_SHIF8;  P0A6L6, NANA_SHIFL;  Q3YX23, NANA_SHISS;  
A7WXZ2, NANA_STAA1;  A6TY99, NANA_STAA2;  Q2FJU9, NANA_STAA3;  
Q2G160, NANA_STAA8;  A5IPI2, NANA_STAA9;  Q2YVB1, NANA_STAAB;  
Q5HJ53, NANA_STAAC;  A6QDU7, NANA_STAAE;  P63949, NANA_STAAM;  
P99123, NANA_STAAN;  Q6GK01, NANA_STAAR;  Q6GCF6, NANA_STAAS;  
A8YZD9, NANA_STAAT;  Q8NYC7, NANA_STAAW;  B9DIJ2, NANA_STACT;  
Q4L9T4, NANA_STAHJ;  Q3B8E8, NPLA_XENLA;  Q5XGL8, NPLB_XENLA;  
Q29RY9, NPL_BOVIN;  Q5ZKD4, NPL_CHICK;  Q6NYR8, NPL_DANRE;  
Q9BXD5, NPL_HUMAN;  Q9DCJ9, NPL_MOUSE;  Q9BEC7, NPL_PIG;  
Q5RDY1, NPL_PONAB;  Q66H59, NPL_RAT;  Q5M905, NPL_XENTR;  

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