ENZYME entry: EC 4.1.3.43

Accepted Name
4-hydroxy-2-oxohexanoate aldolase.
Reaction catalysed
(S)-4-hydroxy-2-oxohexanoate <=> propanal + pyruvate
Cofactor(s)
Mn(2+).
Comment(s)
  • The enzyme from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 4.1.3.39.
  • The enzymes form a bifunctional complex with EC 1.2.1.89 with a tight channel connecting the two subunits.
  • Formerly EC 4.1.3.n1.
Cross-references
BRENDA4.1.3.43
EC2PDB4.1.3.43
ExplorEnz4.1.3.43
PRIAM enzyme-specific profiles4.1.3.43
KEGG Ligand Database for Enzyme Nomenclature4.1.3.43
IUBMB Enzyme Nomenclature4.1.3.43
IntEnz4.1.3.43
MEDLINEFind literature relating to 4.1.3.43
MetaCyc4.1.3.43
UniProtKB/Swiss-Prot
P51015, HOA4_BURXL;  Q53WI0, HOA_THET8;  

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