ID 4.1.99.19 DE 2-iminoacetate synthase. CA L-tyrosine + NADPH + S-adenosyl-L-methionine = 2-iminoacetate + CA 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP(+). CC -!- Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an CC exchangeable S-adenosyl-L-methionine molecule. CC -!- The first stage of catalysis is reduction of the S-adenosyl-L- CC methionine to produce methionine and a 5-deoxyadenosin-5-yl radical CC that is crucial for the conversion of the substrate. CC -!- Part of the pathway for thiamine biosynthesis. CC -!- Formerly EC 1.3.99.n2. DR P30140, THIH_ECOLI ; Q9S498, THIH_SALTY ; //