ENZYME entry: EC 4.2.1.112

Accepted Name
Acetylene hydratase.
Alternative Name(s)
AHy.
Reaction catalysed
Acetaldehyde <=> acetylene + H(2)O
Cofactor(s)
Bis(molybdopterin guanine dinucleotide)molybdenum; Iron-sulfur; W cation.
Comment(s)
  • The tungsten center binds a water molecule that is activated by an adjacent aspartate residue, enabling it to attack acetylene bound in a distinct hydrophobic pocket.
  • Ethylene cannot act as a substrate.
Cross-references
BRENDA4.2.1.112
EC2PDB4.2.1.112
ExplorEnz4.2.1.112
PRIAM enzyme-specific profiles4.2.1.112
KEGG Ligand Database for Enzyme Nomenclature4.2.1.112
IUBMB Enzyme Nomenclature4.2.1.112
IntEnz4.2.1.112
MEDLINEFind literature relating to 4.2.1.112
MetaCyc4.2.1.112
UniProtKB/Swiss-Prot
Q71EW5, AHY_PELAE

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-