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ENZYME entry: EC 220.127.116.11
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|2-methylcitrate dehydratase (2-methyl-trans-aconitate forming).
|(2S,3S)-2-methylcitrate <=> 2-methyl-trans-aconitate + H(2)O|
- Catalyzes the dehydration of (2S,3S)-2-methylcitrate, forming the
trans isomer of 2-methyl-aconitate (unlike EC 18.104.22.168, which forms
only the cis isomer).
- Part of a propanoate degradation pathway.
- The enzyme from Shewanella oneidensis can also accept citrate and
cis-aconitate, but activity with (2S,3S)-2-methylcitrate was
approximately 2.5-fold higher.
- 2-methylisocitrate and isocitrate were not substrates.
|PRIAM enzyme-specific profiles||22.214.171.124|
|KEGG Ligand Database for Enzyme Nomenclature||126.96.36.199|
|IUBMB Enzyme Nomenclature||188.8.131.52|
|MEDLINE||Find literature relating to 184.108.40.206|
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entries corresponding to 4.2.1.-
entries corresponding to 4.2.-.-
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