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ENZYME

ENZYME entry: EC 4.2.1.172

Accepted Name
trans-4-hydroxy-L-proline dehydratase
Reaction catalysed
trans-4-hydroxy-L-proline <=> (S)-1-pyrroline-5-carboxylate + H(+) + H2O
Comment(s)
  • The enzyme has been characterized from the bacterium Peptoclostridium difficile.
  • The active form contains a glycyl radical that is generated by a dedicated activating enzyme via chemistry involving S-adenosyl-L- methionine (SAM) and a [4Fe-4S] cluster.
Cross-references
BRENDA4.2.1.172
EC2PDB4.2.1.172
ExplorEnz4.2.1.172
PRIAM enzyme-specific profiles4.2.1.172
KEGG Ligand Database for Enzyme Nomenclature4.2.1.172
IUBMB Enzyme Nomenclature4.2.1.172
IntEnz4.2.1.172
MEDLINEFind literature relating to 4.2.1.172
MetaCyc4.2.1.172
Rhea expert-curated reactions4.2.1.172
UniProtKB/Swiss-Prot
A0A031WDE4, HYPD_CLODI

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