ENZYME entry: EC 4.2.1.75
| Accepted Name |
|---|
| Uroporphyrinogen-III synthase.
|
| Alternative Name(s) |
|---|
| Hydroxymethylbilane hydro-lyase (cyclizing). |
| Uroporphyrinogen-III cosynthase. |
| Uroporphyrinogen-III cosynthetase. |
| Reaction catalysed |
|---|
| Hydroxymethylbilane <=> uroporphyrinogen III + H(2)O |
| Comment(s) |
|---|
| In the presence of EC 2.5.1.61, forms uroporphyrinogen III from
porphobilinogen.
|
| Cross-references |
|---|
| BRENDA | 4.2.1.75 |
| EC2PDB | 4.2.1.75 |
| ExplorEnz | 4.2.1.75 |
| PRIAM enzyme-specific profiles | 4.2.1.75 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.2.1.75 |
| IUBMB Enzyme Nomenclature | 4.2.1.75 |
| IntEnz | 4.2.1.75 |
| MEDLINE | Find literature relating to 4.2.1.75 |
| MetaCyc | 4.2.1.75 |
| UniProtKB/Swiss-Prot |
| O48721, HEM4_ARATH; | O30120, HEM4_ARCFU; | P21248, HEM4_BACSU; |
| Q59335, HEM4_CHLP8; | Q8KCJ3, HEM4_CHLTE; | Q59294, HEM4_CLOJO; |
| P09126, HEM4_ECOLI; | P10746, HEM4_HUMAN; | Q58401, HEM4_METJA; |
| O26268, HEM4_METTH; | P51163, HEM4_MOUSE; | Q10QR9, HEM4_ORYSJ; |
| Q59683, HEM4_PROMI; | P48246, HEM4_PSEAE; | Q9L6Q3, HEM4_SALTY; |
| P87214, HEM4_SCHPO; | P42452, HEM4_SYNE7; | P06174, HEM4_YEAST; |
|
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