ENZYME entry: EC 4.2.2.3

Accepted Name
Poly(beta-D-mannuronate) lyase.
Alternative Name(s)
Alginate lyase I.
Poly(mana) alginate lyase.
Reaction catalysed
Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their non-reducing ends
Comment(s)
  • The enzyme from the bacterium Sphingomonas sp. strain A1 cleaves alginate producing di- and trisaccharides with an unsaturated uronyl residue at the non-reducing terminus.
  • Formerly EC 4.2.99.4.
Cross-references
BRENDA4.2.2.3
EC2PDB4.2.2.3
ExplorEnz4.2.2.3
PRIAM enzyme-specific profiles4.2.2.3
KEGG Ligand Database for Enzyme Nomenclature4.2.2.3
IUBMB Enzyme Nomenclature4.2.2.3
IntEnz4.2.2.3
MEDLINEFind literature relating to 4.2.2.3
MetaCyc4.2.2.3
UniProtKB/Swiss-Prot
O50660, ALGL_AZOCH;  C1DP89, ALGL_AZOVD;  O52195, ALGL_AZOVI;  
Q9ZNB7, ALGL_COBMA;  A6V1P7, ALGL_PSEA7;  B7UUU9, ALGL_PSEA8;  
Q02R18, ALGL_PSEAB;  Q06749, ALGL_PSEAE;  Q1I563, ALGL_PSEE4;  
Q4KHY5, ALGL_PSEF5;  P59786, ALGL_PSEFL;  C3KDZ3, ALGL_PSEFS;  
A5W8V4, ALGL_PSEP1;  Q3KHR0, ALGL_PSEPF;  B0KGQ9, ALGL_PSEPG;  
Q88ND1, ALGL_PSEPK;  B1J479, ALGL_PSEPW;  Q887Q5, ALGL_PSESM;  
Q9L7P2, ALGL_PSESY;  Q4ZXL0, ALGL_PSEU2;  P39049, ALXM_PHOS4;  
Q59478, ALYA_KLEPN;  Q59639, ALYA_PSEAL;  Q06365, ALYP_PSESO;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-