ID   4.2.3.132
DE   neoabietadiene synthase.
CA   (+)-copalyl diphosphate = diphosphate + neoabietadiene.
CC   -!- Isolated from Abies grandis (grand fir).
CC   -!- This class I enzyme forms about equal proportions of abietadiene,
CC       levopimaradiene and neoabietadiene; see also EC 4.2.3.18 and
CC       EC 4.2.3.32.
CC   -!- An X-ray study of this multifunctional enzyme showed that the class I
CC       activity is in the alpha domain, while EC 5.5.1.12 activity (a class
CC       II activity) is in the beta and gamma domains.
CC   -!- In Pinus taeda (loblolly pine) the major product is levopimaradiene,
CC       with less abietadiene and neoabietadiene.
DR   H8ZM70, LAS_ABIBA  ;  M4HXU6, TPSD1_PINBN;  M4HY05, TPSD1_PINCO;
DR   Q50EK2, TPSD1_PINTA;  M4HYC6, TPSD2_PINCO;  Q38710, TPSDV_ABIGR;
//