ENZYME entry: EC 4.2.3.141

Accepted Name
Sclareol synthase.
Reaction catalysed
(13E)-8-alpha-hydroxylabd-13-en-15-yl diphosphate + H(2)O <=> sclareol + diphosphate
Cofactor(s)
Mn(2+) or Mg(2+).
Comment(s)
  • Isolated from the plant Salvia sclarea (clary sage).
  • Originally thought to be synthesized in one step from geranylgeranyl diphosphate it is now known to require two enzymes, EC 4.2.1.133 and EC 4.2.3.141.
  • Sclareol is used in perfumery.
  • Formerly EC 3.1.7.4.
Cross-references
BRENDA4.2.3.141
EC2PDB4.2.3.141
ExplorEnz4.2.3.141
PRIAM enzyme-specific profiles4.2.3.141
KEGG Ligand Database for Enzyme Nomenclature4.2.3.141
IUBMB Enzyme Nomenclature4.2.3.141
IntEnz4.2.3.141
MEDLINEFind literature relating to 4.2.3.141
MetaCyc4.2.3.141

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-