ID 4.2.3.202 DE hydropyrenol synthase. CA (2E,6E,10E)-geranylgeranyl diphosphate + H2O = diphosphate + CA hydropyrenol. CC -!- Isolated from the bacterium Streptomyces clavuligerus. CC -!- The 1-proR hydrogen atom of geranylgeranyl diphosphate is lost in the CC reaction. CC -!- The enzyme also produces hydropyrene, isoelisabethatriene and traces CC of other diterpenoids. cf. EC 4.2.3.201 and EC 4.2.3.203. //