ID 4.2.3.24 DE amorpha-4,11-diene synthase. AN amorphadiene synthase. CA (2E,6E)-farnesyl diphosphate = (+)-amorpha-4,11-diene + diphosphate. CC -!- A key enzyme in the biosynthesis of the antimalarial endoperoxide CC artemisinin. CC -!- Catalyzes the formation of both olefinic and oxygenated CC sesquiterpenes, with amorpha-4,11-diene being the major product. CC -!- When geranyl diphosphate is used as a substrate, no monoterpenes are CC produced. DR Q9AR04, AMS1_ARTAN ; //