ENZYME entry: EC 4.2.3.37

Accepted Name
Epi-isozizaene synthase.
Reaction catalysed
(2E,6E)-farnesyl diphosphate <=> (+)-epi-isozizaene + diphosphate
Cofactor(s)
Magnesium.
Comment(s)
  • The displacement of the diphosphate group of farnesyl diphosphate occurs with retention of configuration.
  • In the soil-dwelling bacterium Streptomyces coelicolor A3(2), the product of this reaction is used by EC 1.14.13.106 to produce the sesquiterpene antibiotic albaflavenone.
Cross-references
BRENDA4.2.3.37
EC2PDB4.2.3.37
ExplorEnz4.2.3.37
PRIAM enzyme-specific profiles4.2.3.37
KEGG Ligand Database for Enzyme Nomenclature4.2.3.37
IUBMB Enzyme Nomenclature4.2.3.37
IntEnz4.2.3.37
MEDLINEFind literature relating to 4.2.3.37
MetaCyc4.2.3.37
UniProtKB/Swiss-Prot
Q9K499, CYC1_STRCO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-