ENZYME entry: EC 4.3.1.28

Accepted Name
L-lysine cyclodeaminase.
Reaction catalysed
L-lysine <=> L-pipecolate + NH(3)
Cofactor(s)
NAD(+).
Comment(s)
The enzyme produces the non-proteinogenic amino acid L-pipecolate, which is incorporated into multiple secondary metabolite products, including rapamycin, tobulysin, virginiamycin and pristinamycin.
Cross-references
BRENDA4.3.1.28
EC2PDB4.3.1.28
ExplorEnz4.3.1.28
PRIAM enzyme-specific profiles4.3.1.28
KEGG Ligand Database for Enzyme Nomenclature4.3.1.28
IUBMB Enzyme Nomenclature4.3.1.28
IntEnz4.3.1.28
MEDLINEFind literature relating to 4.3.1.28
MetaCyc4.3.1.28
UniProtKB/Swiss-Prot
Q54304, RAPL_STRHY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.1.-
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