ENZYME entry: EC 4.3.3.6

Accepted Name
Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing).
Reaction catalysed
D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine <=> pyridoxal 5'-phosphate + L-glutamate + 3 H(2)O + phosphate
Comment(s)
  • The ammonia is provided by the glutaminase subunit and channeled to the active site of the lyase subunit by a 100 A tunnel.
  • The enzyme can also use ribulose 5-phosphate and dihydroxyacetone phosphate.
  • The enzyme complex is found in aerobic bacteria, archeae, fungi and plants.
Cross-references
BRENDA4.3.3.6
EC2PDB4.3.3.6
ExplorEnz4.3.3.6
PRIAM enzyme-specific profiles4.3.3.6
KEGG Ligand Database for Enzyme Nomenclature4.3.3.6
IUBMB Enzyme Nomenclature4.3.3.6
IntEnz4.3.3.6
MEDLINEFind literature relating to 4.3.3.6
MetaCyc4.3.3.6

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.3.3.-
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