ENZYME entry: EC 4.3.99.2

Accepted Name
Carboxybiotin decarboxylase.
Alternative Name(s)
Carboxybiotin protein decarboxylase.
Reaction catalysed
A carboxybiotinyl-[protein] + 1-2 Na(+)(In) + H(+)(Out) <=> CO(2) + a biotinyl-[protein] + 1-2 Na(+)(Out)
Comment(s)
  • The integral membrane protein MadB from the anaerobic bacterium Malonomonas rubra is a component of the multienzyme complex EC 4.1.1.89.
  • The free energy of the decarboxylation reaction is used to pump Na(+) out of the cell.
Cross-references
BRENDA4.3.99.2
EC2PDB4.3.99.2
ExplorEnz4.3.99.2
PRIAM enzyme-specific profiles4.3.99.2
KEGG Ligand Database for Enzyme Nomenclature4.3.99.2
IUBMB Enzyme Nomenclature4.3.99.2
IntEnz4.3.99.2
MEDLINEFind literature relating to 4.3.99.2
MetaCyc4.3.99.2
UniProtKB/Swiss-Prot
O06923, MADB_MALRU

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