ID   4.99.1.1
DE   Ferrochelatase.
AN   Heme synthase.
AN   Heme synthetase.
AN   Iron chelatase.
AN   Protoheme ferro-lyase.
CA   Protoheme + 2 H(+) = protoporphyrin + Fe(2+).
PR   PROSITE; PDOC00462;
DR   P42043, HEMH1_ARATH;  Q81U22, HEMH1_BACAN;  Q73C98, HEMH1_BACC1;
DR   Q81GW5, HEMH1_BACCR;  Q63ES4, HEMH1_BACCZ;  Q6HM97, HEMH1_BACHK;
DR   Q69TB1, HEMH1_ORYSJ;  Q8EFF4, HEMH1_SHEON;  O04921, HEMH2_ARATH;
DR   Q81TU9, HEMH2_BACAN;  Q73C08, HEMH2_BACC1;  Q81GN7, HEMH2_BACCR;
DR   Q63EK7, HEMH2_BACCZ;  Q6HM28, HEMH2_BACHK;  Q0DIV0, HEMH2_ORYSJ;
DR   Q8EBZ7, HEMH2_SHEON;  Q6F7N0, HEMH_ACIAD ;  B7H0X1, HEMH_ACIB3 ;
DR   B7I4A8, HEMH_ACIB5 ;  B2I2R9, HEMH_ACIBC ;  B0VLE0, HEMH_ACIBS ;
DR   A3M1P7, HEMH_ACIBT ;  B0VEC9, HEMH_ACIBY ;  C1F1C7, HEMH_ACIC5 ;
DR   A3N3M9, HEMH_ACTP2 ;  B3H307, HEMH_ACTP7 ;  B0BTL7, HEMH_ACTPJ ;
DR   A0KL51, HEMH_AERHH ;  Q8U9F7, HEMH_AGRT5 ;  B9JS40, HEMH_AGRVS ;
DR   Q0VSV6, HEMH_ALCBS ;  B6EHK1, HEMH_ALISL ;  Q3MCT9, HEMH_ANAVT ;
DR   B7GF12, HEMH_ANOFW ;  O67083, HEMH_AQUAE ;  Q5P1H1, HEMH_AROAE ;
DR   A1K8P4, HEMH_AZOSB ;  C1DEU1, HEMH_AZOVD ;  Q9KDK9, HEMH_BACHD ;
DR   A8FBM6, HEMH_BACP2 ;  Q5WHT1, HEMH_BACSK ;  P32396, HEMH_BACSU ;
DR   A9VI99, HEMH_BACWK ;  Q6MHT3, HEMH_BDEBA ;  Q7WGI0, HEMH_BORBR ;
DR   Q7W515, HEMH_BORPA ;  Q7VVX8, HEMH_BORPE ;  P22600, HEMH_BOVIN ;
DR   P28602, HEMH_BRAJA ;  A5EBP8, HEMH_BRASB ;  B2SCP3, HEMH_BRUA1 ;
DR   Q2YIS9, HEMH_BRUA2 ;  P0A3D8, HEMH_BRUAB ;  A9MDJ3, HEMH_BRUC2 ;
DR   C0RK28, HEMH_BRUMB ;  P0A3D6, HEMH_BRUME ;  A5VTJ7, HEMH_BRUO2 ;
DR   A9WXE2, HEMH_BRUSI ;  P0A3D7, HEMH_BRUSU ;  B1YTJ5, HEMH_BURA4 ;
DR   Q1BYX9, HEMH_BURCA ;  B1JW14, HEMH_BURCC ;  A0K4S2, HEMH_BURCH ;
DR   Q0BI24, HEMH_BURCM ;  A3MNA4, HEMH_BURM7 ;  A2S570, HEMH_BURM9 ;
DR   Q62HD1, HEMH_BURMA ;  A1V0U1, HEMH_BURMS ;  A3NYY2, HEMH_BURP0 ;
DR   Q3JP06, HEMH_BURP1 ;  A3ND73, HEMH_BURP6 ;  B2JGE7, HEMH_BURP8 ;
DR   B2SXB8, HEMH_BURPP ;  Q63R43, HEMH_BURPS ;  Q39JD2, HEMH_BURS3 ;
DR   Q2SYZ9, HEMH_BURTA ;  A4JBR6, HEMH_BURVG ;  Q145F5, HEMH_BURXL ;
DR   A7ZE60, HEMH_CAMC1 ;  A0RNU4, HEMH_CAMFF ;  A8FKS9, HEMH_CAMJ8 ;
DR   A7H4N6, HEMH_CAMJD ;  Q9PI08, HEMH_CAMJE ;  A1VYL5, HEMH_CAMJJ ;
DR   Q5HVR0, HEMH_CAMJR ;  B8GW40, HEMH_CAUCN ;  P57777, HEMH_CAUCR ;
DR   O42479, HEMH_CHICK ;  Q5L6X6, HEMH_CHLAB ;  Q824K8, HEMH_CHLCV ;
DR   Q252Z7, HEMH_CHLFF ;  Q9PJQ6, HEMH_CHLMU ;  Q9Z7V1, HEMH_CHLPN ;
DR   B0B858, HEMH_CHLT2 ;  Q3KLL2, HEMH_CHLTA ;  B0BCC3, HEMH_CHLTB ;
DR   O84492, HEMH_CHLTR ;  Q7NV65, HEMH_CHRVO ;  Q6NH66, HEMH_CORDI ;
DR   Q8FTB1, HEMH_COREF ;  A4QEC1, HEMH_CORGB ;  Q8NQA1, HEMH_CORGL ;
DR   B6J5R6, HEMH_COXB1 ;  B6J386, HEMH_COXB2 ;  A9KGX9, HEMH_COXBN ;
DR   Q83FA4, HEMH_COXBU ;  A7MNM8, HEMH_CROS8 ;  P42044, HEMH_CUCSA ;
DR   Q0KCJ6, HEMH_CUPNH ;  Q473L7, HEMH_CUPPJ ;  B3R447, HEMH_CUPTR ;
DR   B8HK77, HEMH_CYAP4 ;  B7KGB9, HEMH_CYAP7 ;  B7K399, HEMH_CYAP8 ;
DR   Q47HJ6, HEMH_DECAR ;  Q9RV98, HEMH_DEIRA ;  Q6APB0, HEMH_DESPS ;
DR   Q54IA8, HEMH_DICDI ;  Q9V9S8, HEMH_DROME ;  A7ZIN5, HEMH_ECO24 ;
DR   B7UKF5, HEMH_ECO27 ;  B7MDZ7, HEMH_ECO45 ;  B7L7A0, HEMH_ECO55 ;
DR   Q8XD39, HEMH_ECO57 ;  B5Z3Y6, HEMH_ECO5E ;  B7NIF5, HEMH_ECO7I ;
DR   B7MQJ0, HEMH_ECO81 ;  B7M3W7, HEMH_ECO8A ;  C4ZUS9, HEMH_ECOBW ;
DR   B1XFR2, HEMH_ECODH ;  A7ZXD3, HEMH_ECOHS ;  A1A8E1, HEMH_ECOK1 ;
DR   Q0TKG6, HEMH_ECOL5 ;  Q8FK83, HEMH_ECOL6 ;  B1IZB9, HEMH_ECOLC ;
DR   P23871, HEMH_ECOLI ;  B7N928, HEMH_ECOLU ;  B6I0C7, HEMH_ECOSE ;
DR   B1LJN3, HEMH_ECOSM ;  Q1RF60, HEMH_ECOUT ;  C5BD17, HEMH_EDWI9 ;
DR   A4W7F9, HEMH_ENT38 ;  Q833G5, HEMH_ENTFA ;  Q6D7Z4, HEMH_ERWCT ;
DR   B2VHX1, HEMH_ERWT9 ;  B7LV14, HEMH_ESCF3 ;  Q0RH75, HEMH_FRAAA ;
DR   Q14H85, HEMH_FRAT1 ;  A7NBJ3, HEMH_FRATF ;  Q2A406, HEMH_FRATH ;
DR   B2SDE2, HEMH_FRATM ;  A0Q6Z1, HEMH_FRATN ;  Q0BME1, HEMH_FRATO ;
DR   Q5NFT3, HEMH_FRATT ;  A4IYH5, HEMH_FRATW ;  B5EJ44, HEMH_GEOBB ;
DR   Q5L283, HEMH_GEOKA ;  Q39ZQ5, HEMH_GEOMG ;  B9M326, HEMH_GEOSF ;
DR   Q747F5, HEMH_GEOSL ;  C6E7U2, HEMH_GEOSM ;  C5D6M6, HEMH_GEOSW ;
DR   A4IKU8, HEMH_GEOTN ;  A5GDG7, HEMH_GEOUR ;  Q7NMC7, HEMH_GLOVI ;
DR   Q5FSJ9, HEMH_GLUOX ;  Q4QLD6, HEMH_HAEI8 ;  A5UCU6, HEMH_HAEIE ;
DR   P43868, HEMH_HAEIN ;  C4K332, HEMH_HAMD5 ;  Q17YG0, HEMH_HELAH ;
DR   Q7VHH1, HEMH_HELHP ;  B6JMR9, HEMH_HELP2 ;  B5Z875, HEMH_HELPG ;
DR   Q1CSI9, HEMH_HELPH ;  Q9ZKD4, HEMH_HELPJ ;  B2UUI4, HEMH_HELPS ;
DR   P56107, HEMH_HELPY ;  A9B546, HEMH_HERA2 ;  A4G8D5, HEMH_HERAR ;
DR   P42045, HEMH_HORVU ;  P22830, HEMH_HUMAN ;  Q0BWA5, HEMH_HYPNA ;
DR   Q5QVZ8, HEMH_IDILO ;  A6T228, HEMH_JANMA ;  B5Y0N2, HEMH_KLEP3 ;
DR   Q036X3, HEMH_LACC3 ;  B3W963, HEMH_LACCB ;  Q9CFB4, HEMH_LACLA ;
DR   A2RJS3, HEMH_LACLM ;  Q02Y14, HEMH_LACLS ;  Q88XC3, HEMH_LACPL ;
DR   A5VLS3, HEMH_LACRD ;  B2G944, HEMH_LACRJ ;  Q5X7W3, HEMH_LEGPA ;
DR   A5IHG9, HEMH_LEGPC ;  Q5ZYE7, HEMH_LEGPH ;  Q5WZB4, HEMH_LEGPL ;
DR   Q6AHF2, HEMH_LEIXX ;  B0SF60, HEMH_LEPBA ;  Q8GCV0, HEMH_LEPBI ;
DR   Q04NU7, HEMH_LEPBJ ;  Q04X34, HEMH_LEPBL ;  B0SNJ9, HEMH_LEPBP ;
DR   Q03Z41, HEMH_LEUMM ;  Q929G2, HEMH_LISIN ;  Q71XF4, HEMH_LISMF ;
DR   Q8Y565, HEMH_LISMO ;  Q65SV7, HEMH_MANSM ;  A1U0R2, HEMH_MARAV ;
DR   A6VXF8, HEMH_MARMS ;  Q11ES4, HEMH_MESSB ;  Q607T4, HEMH_METCA ;
DR   Q1H397, HEMH_METFK ;  A2SIR1, HEMH_METPP ;  B8EJ84, HEMH_METSB ;
DR   B0JRN7, HEMH_MICAN ;  P22315, HEMH_MOUSE ;  A0QHT7, HEMH_MYCA1 ;
DR   B1MC29, HEMH_MYCA9 ;  O07401, HEMH_MYCAV ;  P0A577, HEMH_MYCBO ;
DR   A1KIS5, HEMH_MYCBP ;  C1AND1, HEMH_MYCBT ;  A4T9I1, HEMH_MYCGI ;
DR   B8ZS79, HEMH_MYCLB ;  Q9CBM2, HEMH_MYCLE ;  B2HPD6, HEMH_MYCMM ;
DR   Q740Y1, HEMH_MYCPA ;  A0QX29, HEMH_MYCS2 ;  A3PZF2, HEMH_MYCSJ ;
DR   A1UFU2, HEMH_MYCSK ;  Q1B968, HEMH_MYCSS ;  A5U2I9, HEMH_MYCTA ;
DR   P0A576, HEMH_MYCTU ;  A0PNU6, HEMH_MYCUA ;  A1T8R1, HEMH_MYCVP ;
DR   Q5F9U6, HEMH_NEIG1 ;  Q9JVA5, HEMH_NEIMA ;  Q9K097, HEMH_NEIMB ;
DR   A1KSY0, HEMH_NEIMF ;  Q82UK8, HEMH_NITEU ;  Q1QI02, HEMH_NITHX ;
DR   Q3JAW7, HEMH_NITOC ;  A6Q2Y9, HEMH_NITSB ;  Q5YU18, HEMH_NOCFA ;
DR   B2J9P0, HEMH_NOSP7 ;  Q8YQR8, HEMH_NOSS1 ;  Q8ERX9, HEMH_OCEIH ;
DR   A6X6W2, HEMH_OCHA4 ;  B1ZSW3, HEMH_OPITP ;  A2Y3Q5, HEMH_ORYSI ;
DR   Q3YA36, HEMH_PANTR ;  Q6MAW8, HEMH_PARUW ;  P57874, HEMH_PASMU ;
DR   A1ASJ7, HEMH_PELPD ;  Q4FNS1, HEMH_PELUB ;  B4RD10, HEMH_PHEZH ;
DR   Q7N0P6, HEMH_PHOLL ;  Q6LTE0, HEMH_PHOPR ;  Q12BZ9, HEMH_POLSJ ;
DR   B2RHB4, HEMH_PORG3 ;  Q7MXP4, HEMH_PORGI ;  P72183, HEMH_PROFF ;
DR   A3PBP9, HEMH_PROM0 ;  A2C0Y4, HEMH_PROM1 ;  A8G3P0, HEMH_PROM2 ;
DR   A2C7Q7, HEMH_PROM3 ;  A9BEE9, HEMH_PROM4 ;  A2BVI7, HEMH_PROM5 ;
DR   Q31C09, HEMH_PROM9 ;  Q7VD58, HEMH_PROMA ;  B4F1Q1, HEMH_PROMH ;
DR   Q7V6C6, HEMH_PROMM ;  Q7V2F5, HEMH_PROMP ;  A2BQ06, HEMH_PROMS ;
DR   Q46GQ1, HEMH_PROMT ;  Q48MT5, HEMH_PSE14 ;  Q15NQ1, HEMH_PSEA6 ;
DR   A6VC51, HEMH_PSEA7 ;  B7V0K1, HEMH_PSEA8 ;  Q02G19, HEMH_PSEAB ;
DR   Q9HVD7, HEMH_PSEAE ;  Q1IEW1, HEMH_PSEE4 ;  Q4K6B3, HEMH_PSEF5 ;
DR   P57778, HEMH_PSEFC ;  C3KDN7, HEMH_PSEFS ;  A4XR78, HEMH_PSEMY ;
DR   A5VYH6, HEMH_PSEP1 ;  Q3K6Y7, HEMH_PSEPF ;  B0KNF5, HEMH_PSEPG ;
DR   Q88PV4, HEMH_PSEPK ;  B1JER5, HEMH_PSEPW ;  Q888A2, HEMH_PSESM ;
DR   Q4ZXU9, HEMH_PSEU2 ;  A4VKZ1, HEMH_PSEU5 ;  Q4FUR3, HEMH_PSYA2 ;
DR   Q1QDQ5, HEMH_PSYCK ;  A5WH56, HEMH_PSYWF ;  Q1LPN9, HEMH_RALME ;
DR   B2UBQ0, HEMH_RALPJ ;  Q8XW32, HEMH_RALSO ;  B3PZU8, HEMH_RHIE6 ;
DR   Q2K4C4, HEMH_RHIEC ;  Q1MBW8, HEMH_RHIL3 ;  Q98H61, HEMH_RHILO ;
DR   B5ZPG3, HEMH_RHILW ;  Q92M52, HEMH_RHIME ;  Q7UFZ7, HEMH_RHOBA ;
DR   Q59735, HEMH_RHOCA ;  Q2IRD5, HEMH_RHOP2 ;  Q07H58, HEMH_RHOP5 ;
DR   Q6NBF3, HEMH_RHOPA ;  Q13CU0, HEMH_RHOPS ;  B3QF66, HEMH_RHOPT ;
DR   A8GYD7, HEMH_RICB8 ;  Q1RGK5, HEMH_RICBR ;  A8F0B2, HEMH_RICCK ;
DR   Q92FV4, HEMH_RICCN ;  Q4UJN9, HEMH_RICFE ;  Q9ZC84, HEMH_RICPR ;
DR   Q68VM9, HEMH_RICTY ;  B5EXN2, HEMH_SALA4 ;  A9MLY4, HEMH_SALAR ;
DR   Q57S74, HEMH_SALCH ;  B5FLJ9, HEMH_SALDC ;  B5QU78, HEMH_SALEP ;
DR   B5R613, HEMH_SALG2 ;  B4T9I3, HEMH_SALHS ;  B4SWY3, HEMH_SALNS ;
DR   Q5PFJ1, HEMH_SALPA ;  A9MW82, HEMH_SALPB ;  C0PVE1, HEMH_SALPC ;
DR   B5BD43, HEMH_SALPK ;  B4TMG7, HEMH_SALSV ;  Q8Z8T2, HEMH_SALTI ;
DR   P37408, HEMH_SALTY ;  O59786, HEMH_SCHPO ;  A8GAV7, HEMH_SERP5 ;
DR   Q12KR9, HEMH_SHEDO ;  B2U4S8, HEMH_SHIB3 ;  Q325C1, HEMH_SHIBS ;
DR   Q32J55, HEMH_SHIDS ;  Q0T7B0, HEMH_SHIF8 ;  Q83SE5, HEMH_SHIFL ;
DR   Q3Z4S4, HEMH_SHISS ;  Q2NV56, HEMH_SODGM ;  Q5HEU3, HEMH_STAAC ;
DR   P64124, HEMH_STAAM ;  P64125, HEMH_STAAN ;  Q6GFM4, HEMH_STAAR ;
DR   Q6G8A3, HEMH_STAAS ;  P64126, HEMH_STAAW ;  Q5HNA5, HEMH_STAEQ ;
DR   Q8CNS1, HEMH_STAES ;  Q49YM6, HEMH_STAS1 ;  Q82KJ6, HEMH_STRAW ;
DR   O50533, HEMH_STRCO ;  B1VXN6, HEMH_STRGG ;  B4SNS0, HEMH_STRM5 ;
DR   Q8CWW4, HEMH_STRMU ;  Q04KS4, HEMH_STRP2 ;  C1C6Y5, HEMH_STRP7 ;
DR   B1IBG8, HEMH_STRPI ;  B8ZPG2, HEMH_STRPJ ;  Q97R30, HEMH_STRPN ;
DR   B2IPG3, HEMH_STRPS ;  Q8DQ04, HEMH_STRR6 ;  C1CE03, HEMH_STRZJ ;
DR   C1CRD1, HEMH_STRZT ;  Q30S35, HEMH_SULDN ;  B2V955, HEMH_SULSY ;
DR   Q67T48, HEMH_SYMTH ;  Q31S00, HEMH_SYNE7 ;  Q2JVK5, HEMH_SYNJA ;
DR   Q2JHZ4, HEMH_SYNJB ;  B1XL79, HEMH_SYNP2 ;  Q5N2B2, HEMH_SYNP6 ;
DR   A5GJF5, HEMH_SYNPW ;  Q7U5G0, HEMH_SYNPX ;  A5GS98, HEMH_SYNR3 ;
DR   Q0I8L9, HEMH_SYNS3 ;  Q3ALP2, HEMH_SYNSC ;  P54225, HEMH_SYNY3 ;
DR   C5BIF4, HEMH_TERTT ;  Q9HLB8, HEMH_THEAC ;  Q8DGU6, HEMH_THEEB ;
DR   Q72L32, HEMH_THET2 ;  Q978U9, HEMH_THEVO ;  Q31EG9, HEMH_THICR ;
DR   Q3SHA3, HEMH_THIDA ;  B8GU82, HEMH_THISH ;  Q10WR6, HEMH_TRIEI ;
DR   Q83H94, HEMH_TROW8 ;  Q83FJ2, HEMH_TROWT ;  Q9KTB6, HEMH_VIBCH ;
DR   Q5E6Q7, HEMH_VIBF1 ;  B5FBZ6, HEMH_VIBFM ;  Q87RH3, HEMH_VIBPA ;
DR   B7VII4, HEMH_VIBSL ;  Q8DFM2, HEMH_VIBVU ;  Q7MMR4, HEMH_VIBVY ;
DR   Q8D226, HEMH_WIGBR ;  Q73FY6, HEMH_WOLPM ;  B3CLU1, HEMH_WOLPP ;
DR   Q7M7P9, HEMH_WOLSU ;  Q5GRR7, HEMH_WOLTR ;  C0R4L0, HEMH_WOLWR ;
DR   Q8PEX0, HEMH_XANAC ;  Q8P3H6, HEMH_XANCP ;  O57478, HEMH_XENLA ;
DR   B2I7H7, HEMH_XYLF2 ;  Q9PFU1, HEMH_XYLFA ;  B0U456, HEMH_XYLFM ;
DR   Q87B82, HEMH_XYLFT ;  P16622, HEMH_YEAST ;  A1JNA4, HEMH_YERE8 ;
DR   P43413, HEMH_YEREN ;  A7FL85, HEMH_YERP3 ;  Q1C4Q0, HEMH_YERPA ;
DR   B2K6Z7, HEMH_YERPB ;  Q8ZC98, HEMH_YERPE ;  A9R0Q8, HEMH_YERPG ;
DR   Q1CL26, HEMH_YERPN ;  A4TPA3, HEMH_YERPP ;  Q05338, HEMH_YERPS ;
DR   B1JHN0, HEMH_YERPY ;  P57779, HEMH_ZYMMO ;
//