ID   4.99.1.3
DE   Sirohydrochlorin cobaltochelatase.
AN   Anaerobic cobalt chelatase.
AN   Cobaltochelatase.
CA   Cobalt-sirohydrochlorin + 2 H(+) = sirohydrochlorin + Co(2+).
CC   -!- This enzyme is a type II chelatase, being either a monomer (CbiX) or
CC       a homodimer (CibK) and being ATP-independent.
CC   -!- CbiK from Salmonella enterica uses precorrin-2 as the substrate to
CC       yield cobalt-precorrin-2.
CC   -!- The enzyme contains two histidines at the active site that are
CC       thought to be involved in the deprotonation of the tetrapyrrole
CC       substrate as well as in metal binding.
CC   -!- CbiX from Bacillus megaterium inserts cobalt at the level of
CC       sirohydrochlorin (factor-II) rather than precorrin-2.
DR   Q72CB8, CBIKC_DESVH;  Q72EC8, CBIKP_DESVH;  Q05592, CBIK_SALTY ;
DR   O29537, CBIX_ARCFU ;  O87690, CBIX_BACME ;  Q9HQM3, CBIX_HALSA ;
DR   A6UWT5, CBIX_META3 ;  Q8TJZ5, CBIX_METAC ;  P61816, CBIX_METBF ;
DR   Q12X56, CBIX_METBU ;  Q58380, CBIX_METJA ;  Q8TY77, CBIX_METKA ;
DR   Q8PZH6, CBIX_METMA ;  P61819, CBIX_METMP ;  O27448, CBIX_METTH ;
DR   Q4JAI2, CBIX_SULAC ;  C3MZ53, CBIX_SULIA ;  C4KID1, CBIX_SULIK ;
DR   C3MR05, CBIX_SULIL ;  C3MWZ3, CBIX_SULIM ;  C3NGG2, CBIX_SULIN ;
DR   C3N773, CBIX_SULIY ;  Q980A7, CBIX_SULSO ;  Q975N6, CBIX_SULTO ;
DR   Q55451, CBIX_SYNY3 ;
//