ENZYME entry: EC 4.99.1.8
| Accepted Name |
|---|
| Heme ligase.
|
| Alternative Name(s) |
|---|
| Hemozoin synthase. |
| Reaction catalysed |
|---|
| 2 ferriprotoporphyrin IX <=> beta-hematin |
| Comment(s) |
|---|
- This heme detoxifying enzyme is found in Plasmodium parasites and
converts toxic heme to crystalline hemozoin.
- These organisms lack the mammalian heme oxygenase for elimination of
heme.
|
| Cross-references |
|---|
| BRENDA | 4.99.1.8 |
| EC2PDB | 4.99.1.8 |
| ExplorEnz | 4.99.1.8 |
| PRIAM enzyme-specific profiles | 4.99.1.8 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.99.1.8 |
| IUBMB Enzyme Nomenclature | 4.99.1.8 |
| IntEnz | 4.99.1.8 |
| MEDLINE | Find literature relating to 4.99.1.8 |
| MetaCyc | 4.99.1.8 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.99.1.-
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.99.-.-
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-