Expasy logo

ENZYME

ENZYME entry: EC 5.1.3.23

Accepted Name
UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase
Alternative Name(s)
2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerase
UDP-alpha-D-GlcNAc3NAcA 2-epimerase
UDP-GlcNAc3NAcA 2-epimerase
Reaction catalysed
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate <=> UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate
Comment(s)
  • Participates in the biosynthetic pathway for UDP-alpha-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid), an important precursor of the B-band lipopolysaccharide of Pseudomonas aeroginosa serotype O5 and of the band-A trisaccharide of Bordetella pertussis, both important respiratory pathogens.
  • Highly specific as UDP-alpha-D-GlcNAc, UDP-alpha-D-GlcNAcA (UDP-2- acetamido-2-deoxy-alpha-D-glucuronic acid) and UDP-alpha-D-GlcNAc3NAc (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucose) cannot act as substrates.
Cross-references
BRENDA5.1.3.23
EC2PDB5.1.3.23
ExplorEnz5.1.3.23
PRIAM enzyme-specific profiles5.1.3.23
KEGG Ligand Database for Enzyme Nomenclature5.1.3.23
IUBMB Enzyme Nomenclature5.1.3.23
IntEnz5.1.3.23
MEDLINEFind literature relating to 5.1.3.23
MetaCyc5.1.3.23
Rhea expert-curated reactions5.1.3.23
UniProtKB/Swiss-Prot
G3XD61, WBPI_PSEAE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-