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ENZYME entry: EC 5.3.1.28

Accepted Name
D-sedoheptulose 7-phosphate isomerase.
Alternative Name(s)
Phosphoheptose isomerase.
Sedoheptulose-7-phosphate isomerase.
Reaction catalysed
D-sedoheptulose 7-phosphate <=> D-glycero-D-manno-heptose 7-phosphate
Comment(s)
  • In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core.
  • In Gram-positive bacteria the enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein.
Cross-references
BRENDA5.3.1.28
EC2PDB5.3.1.28
ExplorEnz5.3.1.28
PRIAM enzyme-specific profiles5.3.1.28
KEGG Ligand Database for Enzyme Nomenclature5.3.1.28
IUBMB Enzyme Nomenclature5.3.1.28
IntEnz5.3.1.28
MEDLINEFind literature relating to 5.3.1.28
MetaCyc5.3.1.28
UniProtKB/Swiss-Prot
Q9PNE6, GMHA1_CAMJE;  Q9PMN3, GMHA2_CAMJE;  A3N0F8, GMHA_ACTP2;  
B3H1D8, GMHA_ACTP7;  B0BP79, GMHA_ACTPJ;  A6VLR0, GMHA_ACTSZ;  
A0KIK9, GMHA_AERHH;  A4SPH9, GMHA_AERS4;  B2UNE0, GMHA_AKKM8;  
Q0A6I9, GMHA_ALKEH;  B4RXI5, GMHA_ALTMD;  Q9AGY7, GMHA_ANETH;  
O67054, GMHA_AQUAE;  A8EVR5, GMHA_ARCB4;  Q5P6Y3, GMHA_AROAE;  
A1K3T2, GMHA_AZOSB;  C1DQ86, GMHA_AZOVD;  Q2KU87, GMHA_BORA1;  
A5EN81, GMHA_BRASB;  A4YYB9, GMHA_BRASO;  B8D943, GMHA_BUCA5;  
P57338, GMHA_BUCAI;  Q8K9R9, GMHA_BUCAP;  B8D7E7, GMHA_BUCAT;  
Q9AI36, GMHA_BURMA;  Q3JP41, GMHA_BURP1;  Q93UJ2, GMHA_BURPS;  
A7ZE25, GMHA_CAMC1;  A8FMK7, GMHA_CAMJ8;  B9KFJ1, GMHA_CAMLR;  
Q3AUB6, GMHA_CHLCH;  B3EHV1, GMHA_CHLL2;  B3QL68, GMHA_CHLP8;  
A1BJG0, GMHA_CHLPD;  Q8KAW3, GMHA_CHLTE;  Q1QVF5, GMHA_CHRSD;  
Q97EQ4, GMHA_CLOAB;  Q47VU0, GMHA_COLP3;  B6J4R0, GMHA_COXB1;  
B6J2U5, GMHA_COXB2;  A9KBY6, GMHA_COXBN;  A9NAA5, GMHA_COXBR;  
Q83AY4, GMHA_COXBU;  A7MI45, GMHA_CROS8;  B1WYG5, GMHA_CYAA5;  
Q11Y71, GMHA_CYTH3;  Q47IS3, GMHA_DECAR;  C6C0L8, GMHA_DESAD;  
B8J0B1, GMHA_DESDA;  C4XJU6, GMHA_DESMR;  Q72AV1, GMHA_DESVH;  
B8DKW0, GMHA_DESVM;  A7ZHY1, GMHA_ECO24;  B7UJB5, GMHA_ECO27;  
B7MC74, GMHA_ECO45;  B7LHF3, GMHA_ECO55;  P63225, GMHA_ECO57;  
B5Z0M1, GMHA_ECO5E;  B7NKV9, GMHA_ECO7I;  B7MQ59, GMHA_ECO81;  
B7M252, GMHA_ECO8A;  C4ZRV8, GMHA_ECOBW;  B1XD84, GMHA_ECODH;  
A7ZWI6, GMHA_ECOHS;  Q0TL93, GMHA_ECOL5;  P63226, GMHA_ECOL6;  
B1IPP6, GMHA_ECOLC;  P63224, GMHA_ECOLI;  B7N8A8, GMHA_ECOLU;  
B6HZW0, GMHA_ECOSE;  B1LHM8, GMHA_ECOSM;  C5B7W2, GMHA_EDWI9;  
A4W6W5, GMHA_ENT38;  B2VIQ7, GMHA_ERWT9;  B7LW94, GMHA_ESCF3;  
Q8R6A2, GMHA_FUSNN;  B5EGN2, GMHA_GEOBB;  B9M5R7, GMHA_GEODF;  
B3E5N0, GMHA_GEOLS;  Q39X62, GMHA_GEOMG;  Q74BF4, GMHA_GEOSL;  
C6E6C5, GMHA_GEOSM;  A5G5G9, GMHA_GEOUR;  Q0BRW8, GMHA_GRABC;  
O87340, GMHA_HAEDU;  Q4QLB7, GMHA_HAEI8;  A5UCS8, GMHA_HAEIE;  
A5UIU8, GMHA_HAEIG;  P45093, GMHA_HAEIN;  B8F3D3, GMHA_HAEPS;  
A1WYV6, GMHA_HALHL;  C4K7X8, GMHA_HAMD5;  Q7VFZ4, GMHA_HELHP;  
B6JM81, GMHA_HELP2;  Q1CT15, GMHA_HELPH;  Q9ZKZ1, GMHA_HELPJ;  
B2USX3, GMHA_HELPS;  O25528, GMHA_HELPY;  B0USS3, GMHA_HISS2;  
B5Y1F4, GMHA_KLEP3;  A6T518, GMHA_KLEP7;  C1D5I3, GMHA_LARHH;  
B0SHL8, GMHA_LEPBA;  Q04RN4, GMHA_LEPBJ;  Q051Y7, GMHA_LEPBL;  
B0SR27, GMHA_LEPBP;  Q72RC1, GMHA_LEPIC;  Q8F4E9, GMHA_LEPIN;  
Q2WBD9, GMHA_MAGSA;  Q60CC5, GMHA_METCA;  Q58731, GMHA_METJA;  
A2SMC9, GMHA_METPP;  P0A605, GMHA_MYCBO;  A1KET4, GMHA_MYCBP;  
C1AJD9, GMHA_MYCBT;  A5TYI7, GMHA_MYCTA;  P9WGG0, GMHA_MYCTO;  
P9WGG1, GMHA_MYCTU;  Q5F5E3, GMHA_NEIG1;  B4RQP9, GMHA_NEIG2;  
A9M479, GMHA_NEIM0;  P0A0Y5, GMHA_NEIMA;  P0A0Y6, GMHA_NEIMB;  
A1KWG6, GMHA_NEIMF;  A6Q4Z5, GMHA_NITSB;  P57814, GMHA_PASMU;  
Q6D1H3, GMHA_PECAS;  C6DCY7, GMHA_PECCP;  Q3A538, GMHA_PELCD;  
B4SGD2, GMHA_PELPB;  A1AV13, GMHA_PELPD;  Q7N7F7, GMHA_PHOLL;  
B4EUT1, GMHA_PROMH;  A4SGN4, GMHA_PROVI;  Q15PJ1, GMHA_PSEA6;  
A6VB98, GMHA_PSEA7;  B7UZK3, GMHA_PSEA8;  Q02H15, GMHA_PSEAB;  
Q9HVZ0, GMHA_PSEAE;  Q1I5A5, GMHA_PSEE4;  C3KBY0, GMHA_PSEFS;  
A5W8R3, GMHA_PSEP1;  Q3K731, GMHA_PSEPF;  B0KFT9, GMHA_PSEPG;  
B1J1X7, GMHA_PSEPW;  Q4ZNX7, GMHA_PSEU2;  A1SUJ5, GMHA_PSYIN;  
Q2RR43, GMHA_RHORT;  A5UVV6, GMHA_ROSS1;  B5EWJ3, GMHA_SALA4;  
Q57SU4, GMHA_SALCH;  B5FJW2, GMHA_SALDC;  B5R470, GMHA_SALEP;  
B5R5Q7, GMHA_SALG2;  B4T7P3, GMHA_SALHS;  B4SVV2, GMHA_SALNS;  
Q5PF73, GMHA_SALPA;  A9MY16, GMHA_SALPB;  B5BDQ9, GMHA_SALPK;  
B4TYM6, GMHA_SALSV;  P63222, GMHA_SALTI;  P63223, GMHA_SALTY;  
A8GAB6, GMHA_SERP5;  A1SB02, GMHA_SHEAM;  B8EBE0, GMHA_SHEB2;  
A3DA03, GMHA_SHEB5;  A6WTQ0, GMHA_SHEB8;  A9L683, GMHA_SHEB9;  
Q12SK9, GMHA_SHEDO;  Q088R5, GMHA_SHEFN;  B0TL65, GMHA_SHEHH;  
A3Q9E9, GMHA_SHELP;  Q8EK08, GMHA_SHEON;  A8GZ41, GMHA_SHEPA;  
A4YBR9, GMHA_SHEPC;  B8CNK0, GMHA_SHEPW;  A0L231, GMHA_SHESA;  
A8G184, GMHA_SHESH;  Q0HDW8, GMHA_SHESM;  Q0I041, GMHA_SHESR;  
A1RPP6, GMHA_SHESW;  B1KP81, GMHA_SHEWM;  B2U3R4, GMHA_SHIB3;  
Q325S4, GMHA_SHIBS;  Q32JN6, GMHA_SHIDS;  P63227, GMHA_SHIFL;  
Q3Z5B4, GMHA_SHISS;  Q2NVF5, GMHA_SODGM;  Q9Z5B6, GMHA_STRCO;  
Q30T29, GMHA_SULDN;  Q55797, GMHA_SYNY3;  Q9HJV9, GMHA_THEAC;  
Q97A25, GMHA_THEVO;  B5YJT7, GMHA_THEYD;  Q3SMI5, GMHA_THIDA;  
C4LC62, GMHA_TOLAT;  Q9KPY2, GMHA_VIBCH;  Q87MG7, GMHA_VIBPA;  
Q8DBC5, GMHA_VIBVU;  Q7M9U0, GMHA_WOLSU;  A1JP02, GMHA_YERE8;  
A7FLK2, GMHA_YERP3;  Q1C4C6, GMHA_YERPA;  Q8ZBY7, GMHA_YERPE;  
A9R2Y9, GMHA_YERPG;  Q1CLE7, GMHA_YERPN;  A4TPM1, GMHA_YERPP;  
B1JIJ3, GMHA_YERPY;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-