ID   5.3.1.5
DE   xylose isomerase.
AN   D-xylose aldose-ketose-isomerase.
AN   D-xylose isomerase.
AN   D-xylose ketoisomerase.
AN   D-xylose ketol-isomerase.
CA   alpha-D-xylose = alpha-D-xylulofuranose.
CC   -!- Contains two divalent metal ions, preferably magnesium, located at
CC       different metal-binding sites within the active site.
CC   -!- The enzyme catalyzes the interconversion of aldose and ketose sugars
CC       with broad substrate specificity.
CC   -!- The enzyme binds the closed form of its sugar substrate (in the case
CC       of xylose and glucose, only the alpha anomer) and catalyzes ring
CC       opening to generate a form of open-chain conformation that is
CC       coordinated to one of the metal sites.
CC   -!- Isomerization proceeds via a hydride-shift mechanism.
DR   Q8PLL9, XYLA1_XANAC;  Q4UTU6, XYLA1_XANC8;  Q8P9T9, XYLA1_XANCP;
DR   Q5GYQ7, XYLA1_XANOR;  Q8PEW5, XYLA2_XANAC;  Q4UNZ4, XYLA2_XANC8;
DR   Q8P3H1, XYLA2_XANCP;  Q5GUF2, XYLA2_XANOR;  P12851, XYLA_ACTM4 ;
DR   A3N3K2, XYLA_ACTP2 ;  B3H2X9, XYLA_ACTP7 ;  B0BTI9, XYLA_ACTPJ ;
DR   P10654, XYLA_ACTS3 ;  A6VLM8, XYLA_ACTSZ ;  Q8U7G6, XYLA_AGRFC ;
DR   B9JSR6, XYLA_ALLAM ;  Q9FKK7, XYLA_ARATH ;  A0JXN9, XYLA_ARTS2 ;
DR   P12070, XYLA_ARTS7 ;  Q739D2, XYLA_BACC1 ;  Q5LCV9, XYLA_BACFN ;
DR   Q64U20, XYLA_BACFR ;  P77832, XYLA_BACLD ;  A8FE33, XYLA_BACP2 ;
DR   E0TVS5, XYLA_BACSH ;  P0CI80, XYLA_BACSU ;  P54272, XYLA_BACSW ;
DR   Q8A9M2, XYLA_BACTN ;  A7Z522, XYLA_BACVZ ;  A1A0H0, XYLA_BIFAA ;
DR   B3DR33, XYLA_BIFLD ;  Q8G3Q1, XYLA_BIFLO ;  Q89VC7, XYLA_BRADU ;
DR   B2SA37, XYLA_BRUA1 ;  Q2YMQ2, XYLA_BRUA2 ;  A6X4G3, XYLA_BRUA4 ;
DR   Q57EI4, XYLA_BRUAB ;  A9M9H3, XYLA_BRUC2 ;  C0RHQ0, XYLA_BRUMB ;
DR   Q8YFX5, XYLA_BRUME ;  A5VPA1, XYLA_BRUO2 ;  B0CKM9, XYLA_BRUSI ;
DR   Q8G204, XYLA_BRUSU ;  B1Z405, XYLA_BURA4 ;  A0KE56, XYLA_BURCH ;
DR   B4ENA5, XYLA_BURCJ ;  Q0B1U7, XYLA_BURCM ;  A9ARG7, XYLA_BURM1 ;
DR   B1KB47, XYLA_BURO0 ;  Q1BG90, XYLA_BURO1 ;  Q2SW40, XYLA_BURTA ;
DR   A4JSU5, XYLA_BURVG ;  B9MPG8, XYLA_CALBD ;  Q9KGU2, XYLA_CALSX ;
DR   A3PNM4, XYLA_CERS1 ;  Q3IYM4, XYLA_CERS4 ;  A4WVT8, XYLA_CERS5 ;
DR   B9KPP8, XYLA_CERSK ;  Q11EH9, XYLA_CHESB ;  A5CPC1, XYLA_CLAM3 ;
DR   B0RIF1, XYLA_CLAMS ;  A7MNI5, XYLA_CROS8 ;  A8LP53, XYLA_DINSH ;
DR   A7ZTB2, XYLA_ECO24 ;  B7ULC6, XYLA_ECO27 ;  B7MES1, XYLA_ECO45 ;
DR   B7L6Y0, XYLA_ECO55 ;  Q7A9X4, XYLA_ECO57 ;  B5YVL8, XYLA_ECO5E ;
DR   B7NP65, XYLA_ECO7I ;  B7N1L9, XYLA_ECO81 ;  B7M3I8, XYLA_ECO8A ;
DR   C4ZXF6, XYLA_ECOBW ;  B1X8I1, XYLA_ECODH ;  A8A623, XYLA_ECOHS ;
DR   Q0TBN7, XYLA_ECOL5 ;  Q8FCE3, XYLA_ECOL6 ;  B1IZM7, XYLA_ECOLC ;
DR   P00944, XYLA_ECOLI ;  B7NEL7, XYLA_ECOLU ;  B6I3D6, XYLA_ECOSE ;
DR   B1LJC7, XYLA_ECOSM ;  A4W566, XYLA_ENT38 ;  Q7C3R3, XYLA_ENTFA ;
DR   B7LTH9, XYLA_ESCF3 ;  Q6T6K9, XYLA_FERGO ;  Q5KYS6, XYLA_GEOKA ;
DR   P54273, XYLA_GEOSE ;  A4IP67, XYLA_GEOTN ;  Q4QLI2, XYLA_HAEI8 ;
DR   A5UCZ3, XYLA_HAEIE ;  A5UIN7, XYLA_HAEIG ;  P44398, XYLA_HAEIN ;
DR   Q9K993, XYLA_HALH5 ;  B0UT19, XYLA_HISS2 ;  Q40082, XYLA_HORVU ;
DR   P29442, XYLA_KLEPN ;  Q9CFG7, XYLA_LACLA ;  Q02Y75, XYLA_LACLS ;
DR   P21938, XYLA_LACPE ;  Q03TX3, XYLA_LEVBA ;  P29443, XYLA_LEVBR ;
DR   A0AF79, XYLA_LISW6 ;  Q65PY0, XYLA_MANSM ;  A6VWH1, XYLA_MARMS ;
DR   Q2GAB9, XYLA_NOVAD ;  Q8ELU7, XYLA_OCEIH ;  B2JFE9, XYLA_PARP8 ;
DR   B2T929, XYLA_PARPJ ;  Q13RB8, XYLA_PARXL ;  Q6DB05, XYLA_PECAS ;
DR   C6DIH5, XYLA_PECCP ;  Q03HN1, XYLA_PEDPA ;  Q7N4P7, XYLA_PHOLL ;
DR   Q6LUY7, XYLA_PHOPR ;  A6L792, XYLA_PHOV8 ;  O08325, XYLA_PRIM3 ;
DR   Q48J73, XYLA_PSE14 ;  Q15PG0, XYLA_PSEA6 ;  B8HA51, XYLA_PSECP ;
DR   C3K8E3, XYLA_PSEFS ;  Q3KDW0, XYLA_PSEPF ;  Q880Z4, XYLA_PSESM ;
DR   Q4ZSF5, XYLA_PSEU2 ;  B3Q0R5, XYLA_RHIE6 ;  Q2K433, XYLA_RHIEC ;
DR   Q1MBL8, XYLA_RHIJ3 ;  Q98CR8, XYLA_RHILO ;  B5ZQV6, XYLA_RHILW ;
DR   Q92LW9, XYLA_RHIME ;  B9JAF5, XYLA_RHIR8 ;  Q7UVG2, XYLA_RHOBA ;
DR   Q162B6, XYLA_ROSDO ;  Q5LV46, XYLA_RUEPO ;  Q1GKQ4, XYLA_RUEST ;
DR   Q9S306, XYLA_RUMFL ;  B5EX72, XYLA_SALA4 ;  Q57IG0, XYLA_SALCH ;
DR   B5FLD6, XYLA_SALDC ;  B5R4P8, XYLA_SALEP ;  B5RGL6, XYLA_SALG2 ;
DR   B4T952, XYLA_SALHS ;  B4SWK9, XYLA_SALNS ;  Q5PLM6, XYLA_SALPA ;
DR   A9MUV0, XYLA_SALPB ;  C0Q1C2, XYLA_SALPC ;  B4TZ55, XYLA_SALSV ;
DR   Q7C637, XYLA_SALTI ;  Q8ZL90, XYLA_SALTY ;  A8G7W8, XYLA_SERP5 ;
DR   B2U560, XYLA_SHIB3 ;  Q31V53, XYLA_SHIBS ;  Q3YVV0, XYLA_SHISS ;
DR   Q5WKJ3, XYLA_SHOC1 ;  C3M8Y0, XYLA_SINFN ;  A6UD89, XYLA_SINMW ;
DR   Q022S9, XYLA_SOLUE ;  P27157, XYLA_STAXY ;  P24299, XYLA_STRAL ;
DR   Q93HF3, XYLA_STRAW ;  Q9S3Z4, XYLA_STRCK ;  Q9L0B8, XYLA_STRCO ;
DR   P50910, XYLA_STRDI ;  Q9RFM4, XYLA_STRLI ;  P37031, XYLA_STRMR ;
DR   Q93RJ9, XYLA_STROI ;  P15587, XYLA_STROL ;  P22857, XYLA_STRRO ;
DR   P24300, XYLA_STRRU ;  P19149, XYLA_STRS8 ;  Q9L558, XYLA_STRTM ;
DR   P14405, XYLA_STRVN ;  P09033, XYLA_STRVO ;  O82845, XYLA_TETHA ;
DR   P56681, XYLA_THECA ;  Q9X1Z5, XYLA_THEMA ;  P45687, XYLA_THENE ;
DR   B9K7G3, XYLA_THENN ;  A5ILR5, XYLA_THEP1 ;  P22842, XYLA_THEP3 ;
DR   B0K1L3, XYLA_THEPX ;  P30435, XYLA_THESA ;  B1LB08, XYLA_THESQ ;
DR   P26997, XYLA_THET8 ;  P29441, XYLA_THETC ;  P19148, XYLA_THETU ;
DR   Q3BMF2, XYLA_XANC5 ;  Q2NXR2, XYLA_XANOM ;  A1JT10, XYLA_YERE8 ;
DR   A7FP68, XYLA_YERP3 ;  Q1C0D3, XYLA_YERPA ;  B2K7D2, XYLA_YERPB ;
DR   Q8Z9Z1, XYLA_YERPE ;  A9R5Q1, XYLA_YERPG ;  Q1CDB8, XYLA_YERPN ;
DR   A4TS63, XYLA_YERPP ;  Q663Y3, XYLA_YERPS ;  B1JH40, XYLA_YERPY ;
//