ENZYME entry: EC 5.4.3.9

Accepted Name
Glutamate 2,3-aminomutase.
Reaction catalysed
L-glutamate <=> 3-aminopentanedioate
Cofactor(s)
Iron-sulfur; Pyridoxal 5'-phosphate; S-adenosyl-L-methionine.
Comment(s)
  • This enzyme is a member of the 'AdoMet radical' (radical SAM) family.
  • It contains pyridoxal phosphate and a [4Fe-4S] cluster, which is coordinated by 3 cysteines and binds an exchangeable S-adenosyl-L- methionine molecule.
  • During the reaction cycle, the AdoMet forms a 5'-deoxyadenosyl radical, which is regenerated at the end of the reaction.
Cross-references
BRENDA5.4.3.9
EC2PDB5.4.3.9
ExplorEnz5.4.3.9
PRIAM enzyme-specific profiles5.4.3.9
KEGG Ligand Database for Enzyme Nomenclature5.4.3.9
IUBMB Enzyme Nomenclature5.4.3.9
IntEnz5.4.3.9
MEDLINEFind literature relating to 5.4.3.9
MetaCyc5.4.3.9
UniProtKB/Swiss-Prot
Q185C5, EAM_PEPD6

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.-.-.-