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ENZYME entry: EC 5.4.99.19

Accepted Name
16S rRNA pseudouridine(516) synthase.
Alternative Name(s)
16S RNA pseudouridine 516 synthase.
16S RNA pseudouridine(516) synthase.
16S RNA Psi(516) synthase.
Reaction catalysed
16S rRNA uridine(516) <=> 16S rRNA pseudouridine(516)
Comment(s)
  • The enzyme is specific for uridine(516) in 16S rRNA.
  • In vitro, the enzyme does not modify free 16S rRNA.
  • The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins.
Cross-references
BRENDA5.4.99.19
EC2PDB5.4.99.19
ExplorEnz5.4.99.19
PRIAM enzyme-specific profiles5.4.99.19
KEGG Ligand Database for Enzyme Nomenclature5.4.99.19
IUBMB Enzyme Nomenclature5.4.99.19
IntEnz5.4.99.19
MEDLINEFind literature relating to 5.4.99.19
MetaCyc5.4.99.19
UniProtKB/Swiss-Prot
P0AA45, RSUA_ECO57;  P0AA44, RSUA_ECOL6;  P0AA43, RSUA_ECOLI;  
P45124, RSUA_HAEIN;  Q9CPN4, RSUA_PASMU;  Q9I5J6, RSUA_PSEAE;  
P65841, RSUA_SALTI;  P65840, RSUA_SALTY;  P0AA46, RSUA_SHIFL;  
Q9KRK5, RSUA_VIBCH;  Q87QD4, RSUA_VIBPA;  Q8D8X2, RSUA_VIBVU;  
Q8ZGM2, RSUA_YERPE;  

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