ID 5.4.99.45 DE tRNA pseudouridine(38/39) synthase. AN pseudouridine synthase 3. CA uridine(38/39) in tRNA = pseudouridine(38/39) in tRNA. CC -!- The enzyme from Saccharomyces cerevisiae is active only toward CC uridine(38) and uridine(39), and shows no activity with uridine(40) CC (cf. EC 5.4.99.12). CC -!- In vitro the enzyme from mouse is active on uridine(39) and very CC slightly on uridine(38) (human tRNA(Leu)). DR Q3SX07, PUS3_BOVIN ; Q9BZE2, PUS3_HUMAN ; Q9JI38, PUS3_MOUSE ; DR P31115, PUS3_YEAST ; //