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ENZYME

ENZYME entry: EC 5.4.99.61

Accepted Name
precorrin-8X methylmutase
Alternative Name(s)
HBA synthase
hydrogenobyrinic acid-binding protein
precorrin isomerase
Reaction catalysed
3 H(+) + precorrin-8X <=> hydrogenobyrinate
Comment(s)
  • The enzyme, which participates in the aerobic (late cobalt insertion) adenosylcobalamin biosynthesis pathway, catalyzes the conversion of precorrin-8X to hydrogenobyrinate by methyl rearrangement.
  • The equivalent enzyme in the anaerobic pathway is EC 5.4.99.60.
  • Formerly EC 5.4.1.2.
Cross-references
BRENDA5.4.99.61
EC2PDB5.4.99.61
ExplorEnz5.4.99.61
PRIAM enzyme-specific profiles5.4.99.61
KEGG Ligand Database for Enzyme Nomenclature5.4.99.61
IUBMB Enzyme Nomenclature5.4.99.61
IntEnz5.4.99.61
MEDLINEFind literature relating to 5.4.99.61
MetaCyc5.4.99.61
Rhea expert-curated reactions5.4.99.61
UniProtKB/Swiss-Prot
P63840, COBH_MYCBOP9WP86, COBH_MYCTOP9WP87, COBH_MYCTU
Q9HZU2, COBH_PSEAEP21638, COBH_SINSX

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