ENZYME entry: EC 5.5.1.14

Accepted Name
Syn-copalyl-diphosphate synthase.
Alternative Name(s)
Syn-copalyl diphosphate synthase.
Syn-CPP synthase.
Reaction catalysed
Geranylgeranyl diphosphate <=> 9-alpha-copalyl diphosphate
Cofactor(s)
Mg(2+).
Comment(s)
  • This class II terpene synthase produces syn-copalyl diphosphate, a precursor of several rice phytoalexins, including oryzalexin S and momilactones A and B.
  • Phytoalexins are diterpenoid secondary metabolites that are involved in the defense mechanism of the plant, and are produced in response to pathogen attack through the perception of elicitor signal molecules such as chitin oligosaccharide, or after exposure to UV irradiation.
  • Constitutively expressed in the roots of plants where one of its products, momilactone B, acts as an allelochemical (a molecule released into the environment to suppress the growth of neighboring plants).
  • In other tissues the enzyme is up-regulated by conditions that stimulate the biosynthesis of phytoalexins.
Cross-references
BRENDA5.5.1.14
EC2PDB5.5.1.14
ExplorEnz5.5.1.14
PRIAM enzyme-specific profiles5.5.1.14
KEGG Ligand Database for Enzyme Nomenclature5.5.1.14
IUBMB Enzyme Nomenclature5.5.1.14
IntEnz5.5.1.14
MEDLINEFind literature relating to 5.5.1.14
MetaCyc5.5.1.14
UniProtKB/Swiss-Prot
Q96WT2, ACS_PLEBE;  Q6E7D7, CPS4_ORYSI;  Q0JF02, CPS4_ORYSJ;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.5.1.-
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