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ENZYME

ENZYME entry: EC 5.5.1.23

Accepted Name
aklanonic acid methyl ester cyclase
Alternative Name(s)
methyl aklanonate cyclase
Reaction catalysed
methyl aklanonate <=> aklaviketone
Comment(s)
The enzyme is involved in the biosynthesis of aklaviketone, an intermediate in the biosynthetic pathways leading to formation of several anthracycline antibiotics, including aclacinomycin, daunorubicin and doxorubicin.
Cross-references
BRENDA5.5.1.23
EC2PDB5.5.1.23
ExplorEnz5.5.1.23
PRIAM enzyme-specific profiles5.5.1.23
KEGG Ligand Database for Enzyme Nomenclature5.5.1.23
IUBMB Enzyme Nomenclature5.5.1.23
IntEnz5.5.1.23
MEDLINEFind literature relating to 5.5.1.23
MetaCyc5.5.1.23
Rhea expert-curated reactions5.5.1.23
UniProtKB/Swiss-Prot
O52646, DNRD_STRGJQ54808, DNRD_STRPEQ55215, DNRD_STRS5

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