ID   6.1.1.23
DE   aspartate--tRNA(Asn) ligase.
AN   nondiscriminating aspartyl-tRNA synthetase.
CA   ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx).
CC   -!- When this enzyme acts on tRNA(Asp), it catalyzes the same reaction as
CC       EC 6.1.1.12.
CC   -!- It has, however, diminished discrimination, so that it can also form
CC       aspartyl-tRNA(Asn).
CC   -!- This relaxation of specificity has been found to result from the
CC       absence of a loop in the tRNA that specifically recognizes the third
CC       position of the anticodon.
CC   -!- This accounts for the ability of this enzyme in, for example, Thermus
CC       thermophilus, to recognize both tRNA(Asp) (GUC anticodon) and
CC       tRNA(Asn) (GUU anticodon).
CC   -!- The aspartate-tRNA(Asn) is not used in protein synthesis until it is
CC       converted by EC 6.3.5.6 into asparaginyl-tRNA(Asn).
DR   Q2LPW5, SYDN1_SYNAS;  Q2LTE0, SYDN2_SYNAS;  B0CF01, SYDND_ACAM1;
DR   Q6FEH6, SYDND_ACIAD;  B7GWN1, SYDND_ACIB3;  B7I8M5, SYDND_ACIB5;
DR   B2HYL7, SYDND_ACIBC;  B0VRC7, SYDND_ACIBS;  A3M8Q6, SYDND_ACIBT;
DR   B0V550, SYDND_ACIBY;  A0LUJ6, SYDND_ACIC1;  C1FAE8, SYDND_ACIC5;
DR   A5G126, SYDND_ACICJ;  B9ME28, SYDND_ACIET;  B7J3F7, SYDND_ACIF2;
DR   B5EJL3, SYDND_ACIF5;  A1W4E1, SYDND_ACISJ;  Q9Y9U7, SYDND_AERPE;
DR   B6JGJ7, SYDND_AFIC5;  Q8UG87, SYDND_AGRFC;  Q21YX2, SYDND_ALBFT;
DR   Q0VRK1, SYDND_ALCBS;  A8ESW7, SYDND_ALIB4;  Q0A582, SYDND_ALKEH;
DR   B9JV61, SYDND_ALLAM;  B8JH60, SYDND_ANAD2;  Q2IKX7, SYDND_ANADE;
DR   B9KHS0, SYDND_ANAMF;  Q2GLD8, SYDND_ANAPZ;  B4UIE3, SYDND_ANASK;
DR   B7GFR1, SYDND_ANOFW;  O67589, SYDND_AQUAE;  O29342, SYDND_ARCFU;
DR   Q5P280, SYDND_AROAE;  A0JXA1, SYDND_ARTS2;  A8IFX1, SYDND_AZOC5;
DR   A1KAJ9, SYDND_AZOSB;  C1DRG2, SYDND_AZOVD;  C3P990, SYDND_BACAA;
DR   C3L608, SYDND_BACAC;  A0RJ11, SYDND_BACAH;  Q81LI7, SYDND_BACAN;
DR   B7JPY8, SYDND_BACC0;  Q730D1, SYDND_BACC1;  B7IIR4, SYDND_BACC2;
DR   C1ESU7, SYDND_BACC3;  B7HE37, SYDND_BACC4;  B7HQG0, SYDND_BACC7;
DR   A7GT84, SYDND_BACCN;  B9IYX5, SYDND_BACCQ;  Q817X8, SYDND_BACCR;
DR   Q634E3, SYDND_BACCZ;  Q6HDC3, SYDND_BACHK;  A9VIM8, SYDND_BACMK;
DR   O32038, SYDND_BACSU;  A7Z750, SYDND_BACVZ;  A1UT52, SYDND_BARBK;
DR   Q6G330, SYDND_BARHE;  Q6FZI4, SYDND_BARQU;  A9IVI2, SYDND_BART1;
DR   Q6MI59, SYDND_BDEBA;  B2IKA4, SYDND_BEII9;  C5C5S1, SYDND_BEUC1;
DR   B3DPM0, SYDND_BIFLD;  Q8G863, SYDND_BIFLO;  B7GPT0, SYDND_BIFLS;
DR   Q2L1K6, SYDND_BORA1;  Q0SN63, SYDND_BORAP;  Q7WR42, SYDND_BORBR;
DR   O51402, SYDND_BORBU;  B7J213, SYDND_BORBZ;  B5RM04, SYDND_BORDL;
DR   Q661H4, SYDND_BORGP;  B2S0F0, SYDND_BORHD;  Q7W275, SYDND_BORPA;
DR   A9IHE2, SYDND_BORPD;  Q7W001, SYDND_BORPE;  B5RRQ0, SYDND_BORRA;
DR   A1QZN3, SYDND_BORT9;  Q89MP9, SYDND_BRADU;  C0R2C9, SYDND_BRAHW;
DR   A5EIE6, SYDND_BRASB;  A4YTC4, SYDND_BRASO;  B2S501, SYDND_BRUA1;
DR   Q2YNA7, SYDND_BRUA2;  A6X200, SYDND_BRUA4;  Q57DZ8, SYDND_BRUAB;
DR   A9MAD3, SYDND_BRUC2;  C0RI89, SYDND_BRUMB;  P67012, SYDND_BRUME;
DR   A5VPT5, SYDND_BRUO2;  B0CL77, SYDND_BRUSI;  P67013, SYDND_BRUSU;
DR   B1YWF2, SYDND_BURA4;  A0KAE8, SYDND_BURCH;  B4EBD1, SYDND_BURCJ;
DR   Q0BBZ1, SYDND_BURCM;  Q39D20, SYDND_BURL3;  A9AFC7, SYDND_BURM1;
DR   A3MNU6, SYDND_BURM7;  A2S8L9, SYDND_BURM9;  Q62MP0, SYDND_BURMA;
DR   A1V745, SYDND_BURMS;  B1JYI9, SYDND_BURO0;  Q1BTP1, SYDND_BURO1;
DR   A3NRK2, SYDND_BURP0;  Q3JVY8, SYDND_BURP1;  A3N5V6, SYDND_BURP6;
DR   Q63X93, SYDND_BURPS;  Q2T132, SYDND_BURTA;  A4JHR9, SYDND_BURVG;
DR   Q8RAI7, SYDND_CALS4;  A7ZEH3, SYDND_CAMC1;  A0RQ71, SYDND_CAMFF;
DR   A7I058, SYDND_CAMHC;  A8FL61, SYDND_CAMJ8;  A7H4H2, SYDND_CAMJD;
DR   Q9PHM7, SYDND_CAMJE;  A1VZ00, SYDND_CAMJJ;  Q5HVD1, SYDND_CAMJR;
DR   Q3AA17, SYDND_CARHZ;  B0SWQ6, SYDND_CAUSK;  Q9A734, SYDND_CAUVC;
DR   B3PB55, SYDND_CELJU;  A3PMK8, SYDND_CERS1;  Q3IZP1, SYDND_CERS4;
DR   A4WPF7, SYDND_CERS5;  B9KME7, SYDND_CERSK;  Q11JA7, SYDND_CHESB;
DR   A9WGJ7, SYDND_CHLAA;  Q5L734, SYDND_CHLAB;  B8G6W9, SYDND_CHLAD;
DR   Q3AS30, SYDND_CHLCH;  Q46175, SYDND_CHLCV;  B3EDE5, SYDND_CHLL2;
DR   Q3B3A1, SYDND_CHLL3;  Q9PJK0, SYDND_CHLMU;  B3QP90, SYDND_CHLP8;
DR   B3EQ26, SYDND_CHLPB;  A1BGZ4, SYDND_CHLPD;  A4SF07, SYDND_CHLPM;
DR   Q9Z7P2, SYDND_CHLPN;  B9LJ78, SYDND_CHLSY;  B0B8B6, SYDND_CHLT2;
DR   Q3KLF5, SYDND_CHLTA;  B0B9Z5, SYDND_CHLTB;  Q8KCT7, SYDND_CHLTE;
DR   O84546, SYDND_CHLTR;  Q1QWG2, SYDND_CHRSD;  Q7NRP0, SYDND_CHRVO;
DR   B5EIV1, SYDND_CITBB;  Q483C7, SYDND_COLP3;  C3PGN5, SYDND_CORA7;
DR   Q6NGZ4, SYDND_CORDI;  Q8FT19, SYDND_COREF;  A4QEL0, SYDND_CORGB;
DR   Q8NQ19, SYDND_CORGL;  Q4JVF2, SYDND_CORJK;  C4LIW2, SYDND_CORK4;
DR   B1VDL1, SYDND_CORU7;  A9KF44, SYDND_COXBN;  A9N999, SYDND_COXBR;
DR   Q83BE5, SYDND_COXBU;  B1WRQ9, SYDND_CROS5;  Q1LRG2, SYDND_CUPMC;
DR   Q0KEG8, SYDND_CUPNH;  Q475W2, SYDND_CUPPJ;  B2AH15, SYDND_CUPTR;
DR   Q6A8J1, SYDND_CUTAK;  B8HXQ8, SYDND_CYAP4;  Q47IE0, SYDND_DECAR;
DR   Q3Z8K0, SYDND_DEHM1;  A5FRE3, SYDND_DEHMB;  Q3ZX84, SYDND_DEHMC;
DR   Q9RVH4, SYDND_DEIRA;  A9BP37, SYDND_DELAS;  C0QFI1, SYDND_DESAH;
DR   B8FKS6, SYDND_DESAL;  A8ZUR7, SYDND_DESOH;  Q6AQS4, SYDND_DESPS;
DR   A4J2J2, SYDND_DESRM;  Q725Q7, SYDND_DESVH;  B5YDT0, SYDND_DICT6;
DR   B8E1C0, SYDND_DICTD;  A8LI32, SYDND_DINSH;  Q3YRF1, SYDND_EHRCJ;
DR   Q2GHC9, SYDND_EHRCR;  Q5FG09, SYDND_EHRRG;  Q5HAL5, SYDND_EHRRW;
DR   B2KBB9, SYDND_ELUMP;  B1GZY6, SYDND_ENDTX;  Q2NBQ6, SYDND_ERYLH;
DR   B0TW08, SYDND_FRAP2;  A7N949, SYDND_FRATF;  Q2A622, SYDND_FRATH;
DR   Q0BPA2, SYDND_FRATO;  Q5NIQ4, SYDND_FRATT;  A4J0C7, SYDND_FRATW;
DR   B9M1C9, SYDND_GEODF;  Q39VY3, SYDND_GEOMG;  Q74D56, SYDND_GEOSL;
DR   C6E3W7, SYDND_GEOSM;  C5D509, SYDND_GEOSW;  A5G3L5, SYDND_GEOUR;
DR   B7KB89, SYDND_GLOC7;  Q7NJA4, SYDND_GLOVI;  Q5FQ60, SYDND_GLUOX;
DR   Q2SCK8, SYDND_HAHCH;  Q5V1N2, SYDND_HALMA;  B8CXE5, SYDND_HALOH;
DR   O07683, SYDND_HALSA;  O24822, SYDND_HALVO;  Q18KP5, SYDND_HALWD;
DR   Q17XK9, SYDND_HELAH;  Q7VF76, SYDND_HELHP;  B0TF89, SYDND_HELMI;
DR   B6JLK1, SYDND_HELP2;  B5Z6Y8, SYDND_HELPG;  Q1CTQ7, SYDND_HELPH;
DR   Q9ZLL9, SYDND_HELPJ;  B2UTL0, SYDND_HELPS;  P56459, SYDND_HELPY;
DR   A9B392, SYDND_HERA2;  A4G8X1, SYDND_HERAR;  Q31H87, SYDND_HYDCU;
DR   B4U7P3, SYDND_HYDS0;  Q0BZZ1, SYDND_HYPNA;  Q28MH9, SYDND_JANSC;
DR   A6WCG5, SYDND_KINRD;  A9KIA6, SYDND_LACP7;  C1DB91, SYDND_LARHH;
DR   Q5X586, SYDND_LEGPA;  A5IBW8, SYDND_LEGPC;  Q5ZVG2, SYDND_LEGPH;
DR   Q5WWA3, SYDND_LEGPL;  B1XWR8, SYDND_LEPCP;  A0L667, SYDND_MAGMM;
DR   Q2W3D5, SYDND_MAGSA;  Q0AQ87, SYDND_MARMM;  A6VXD0, SYDND_MARMS;
DR   A1U1C2, SYDND_MARN8;  A6USZ9, SYDND_META3;  Q8TQ68, SYDND_METAC;
DR   Q466Y5, SYDND_METBF;  Q12XU7, SYDND_METBU;  B7KN33, SYDND_METC4;
DR   Q607I4, SYDND_METCA;  Q1GYN8, SYDND_METFK;  Q2FRU5, SYDND_METHJ;
DR   B3DX01, SYDND_METI4;  Q58950, SYDND_METJA;  Q8TXG4, SYDND_METKA;
DR   A2SPG1, SYDND_METLZ;  A4G0V5, SYDND_METM5;  A9A945, SYDND_METM6;
DR   A6VHK5, SYDND_METM7;  Q8Q0R2, SYDND_METMA;  A3CXH4, SYDND_METMJ;
DR   Q6LWU0, SYDND_METMP;  B8IUT2, SYDND_METNO;  B1ZFX6, SYDND_METPB;
DR   A2SEP2, SYDND_METPP;  B0UI66, SYDND_METS4;  B8EN55, SYDND_METSB;
DR   Q2NHT0, SYDND_METST;  O26328, SYDND_METTH;  A6UQQ8, SYDND_METVS;
DR   B0JNW9, SYDND_MICAN;  C5CCH2, SYDND_MICLC;  Q2RHW1, SYDND_MOOTA;
DR   A0QI91, SYDND_MYCA1;  B1MCH3, SYDND_MYCA9;  Q7TYA6, SYDND_MYCBO;
DR   A4TBU4, SYDND_MYCGI;  B8ZUJ3, SYDND_MYCLB;  P36429, SYDND_MYCLE;
DR   Q741M7, SYDND_MYCPA;  A0QWN3, SYDND_MYCS2;  A3PZ05, SYDND_MYCSJ;
DR   A1UFE5, SYDND_MYCSK;  P9WFW2, SYDND_MYCTO;  P9WFW3, SYDND_MYCTU;
DR   Q3IT59, SYDND_NATPD;  B2A2G0, SYDND_NATTJ;  B4RPA1, SYDND_NEIG2;
DR   A9M257, SYDND_NEIM0;  Q9JT23, SYDND_NEIMA;  Q9K0U5, SYDND_NEIMB;
DR   A1KVG2, SYDND_NEIMF;  Q0AIE4, SYDND_NITEC;  Q82SQ5, SYDND_NITEU;
DR   Q1QLI9, SYDND_NITHX;  Q2YBG1, SYDND_NITMU;  Q3JEB6, SYDND_NITOC;
DR   Q3SS92, SYDND_NITWN;  Q5YTJ4, SYDND_NOCFA;  A1SJB8, SYDND_NOCSJ;
DR   B2J116, SYDND_NOSP7;  Q8YUB6, SYDND_NOSS1;  Q2G8P1, SYDND_NOVAD;
DR   Q317R3, SYDND_OLEA2;  B1ZSW8, SYDND_OPITP;  A5CC91, SYDND_ORITB;
DR   B3CV53, SYDND_ORITI;  A1TT99, SYDND_PARC0;  A1B431, SYDND_PARDP;
DR   A7HYC4, SYDND_PARL1;  Q7U3K6, SYDND_PARMW;  B2JCV5, SYDND_PARP8;
DR   B2SX42, SYDND_PARPJ;  Q6ME91, SYDND_PARUW;  Q145N3, SYDND_PARXL;
DR   B4SAH1, SYDND_PELPB;  A5D3E3, SYDND_PELTS;  Q4FMP8, SYDND_PELUB;
DR   C0QT74, SYDND_PERMH;  B4RCT1, SYDND_PHEZH;  B1XNY9, SYDND_PICP2;
DR   B4S8V2, SYDND_PROA2;  A3PFH7, SYDND_PROM0;  A8G7J3, SYDND_PROM2;
DR   A2CDX5, SYDND_PROM3;  A9BDD8, SYDND_PROM4;  A2BZ75, SYDND_PROM5;
DR   Q317V3, SYDND_PROM9;  Q7V9I1, SYDND_PROMA;  Q7V3X1, SYDND_PROMM;
DR   Q7UZH8, SYDND_PROMP;  A2BTS0, SYDND_PROMS;  Q46I98, SYDND_PROMT;
DR   Q48FC1, SYDND_PSE14;  Q15RN2, SYDND_PSEA6;  B7UXW9, SYDND_PSEA8;
DR   Q02IC5, SYDND_PSEAB;  Q51422, SYDND_PSEAE;  B8H9C7, SYDND_PSECP;
DR   Q1I6E5, SYDND_PSEE4;  Q4K7D5, SYDND_PSEF5;  C3JYT1, SYDND_PSEFS;
DR   A4XRR7, SYDND_PSEMY;  A5VZU3, SYDND_PSEP1;  Q3K7V6, SYDND_PSEPF;
DR   B0KTJ6, SYDND_PSEPG;  Q88NJ4, SYDND_PSEPK;  B1JD74, SYDND_PSEPW;
DR   Q87Y31, SYDND_PSESM;  Q4ZWL5, SYDND_PSEU2;  Q4FSF4, SYDND_PSYA2;
DR   Q1QBI9, SYDND_PSYCK;  A1SST6, SYDND_PSYIN;  A5WE50, SYDND_PSYWF;
DR   Q8Y270, SYDND_RALN1;  Q1MIW0, SYDND_RHIJ3;  Q983E9, SYDND_RHILO;
DR   B5ZX21, SYDND_RHILW;  Q92QV4, SYDND_RHIME;  B9JCV9, SYDND_RHIR8;
DR   Q7UFY6, SYDND_RHOBA;  B6IN46, SYDND_RHOCS;  C0ZZA3, SYDND_RHOE4;
DR   Q0S0P3, SYDND_RHOJR;  C1B4G8, SYDND_RHOOB;  Q2IX59, SYDND_RHOP2;
DR   Q07LH5, SYDND_RHOP5;  Q6N5D6, SYDND_RHOPA;  Q215P7, SYDND_RHOPB;
DR   Q135R5, SYDND_RHOPS;  B3Q9Q1, SYDND_RHOPT;  Q2RSM3, SYDND_RHORT;
DR   C3PMI3, SYDND_RICAE;  A8GMB3, SYDND_RICAH;  A8GXC5, SYDND_RICB8;
DR   Q1RJN4, SYDND_RICBR;  A8EXL4, SYDND_RICCK;  Q92J82, SYDND_RICCN;
DR   Q4UKE2, SYDND_RICFE;  Q9ZE17, SYDND_RICPR;  Q68XM3, SYDND_RICTY;
DR   B7JX16, SYDND_RIPO1;  A7NQH9, SYDND_ROSCS;  Q16B16, SYDND_ROSDO;
DR   A5UUR3, SYDND_ROSS1;  Q1AWB4, SYDND_RUBXD;  Q5LUX6, SYDND_RUEPO;
DR   Q1GIZ8, SYDND_RUEST;  A1AW56, SYDND_RUTMC;  Q21MA4, SYDND_SACD2;
DR   A4FBC3, SYDND_SACEN;  Q980V3, SYDND_SACS2;  A8LXY1, SYDND_SALAI;
DR   Q2S158, SYDND_SALRD;  A4X5Y3, SYDND_SALTO;  C3M9G8, SYDND_SINFN;
DR   A6U7M8, SYDND_SINMW;  Q8DSG3, SYDND_STRMU;  Q30RL7, SYDND_SULDN;
DR   A6QAE8, SYDND_SULNB;  B2V713, SYDND_SULSY;  Q976I3, SYDND_SULTO;
DR   Q67LP0, SYDND_SYMTH;  Q3A5R7, SYDND_SYNC1;  Q31NM6, SYDND_SYNE7;
DR   Q2JTZ2, SYDND_SYNJA;  Q2JMA8, SYDND_SYNJB;  Q5N5I8, SYDND_SYNP6;
DR   A5GPL9, SYDND_SYNPW;  A5GWT2, SYDND_SYNR3;  Q3AVS9, SYDND_SYNS9;
DR   Q3AGF9, SYDND_SYNSC;  Q0AYS1, SYDND_SYNWW;  P73851, SYDND_SYNY3;
DR   C5BPP4, SYDND_TERTT;  Q47N50, SYDND_THEFY;  Q9X1F4, SYDND_THEMA;
DR   B9K8E5, SYDND_THENN;  B0K978, SYDND_THEP3;  B0K0N5, SYDND_THEPX;
DR   B1LBH9, SYDND_THESQ;  Q5SIC2, SYDND_THET8;  Q8DJS8, SYDND_THEVB;
DR   B5YJP5, SYDND_THEYD;  Q3SLL2, SYDND_THIDA;  B8GUK0, SYDND_THISH;
DR   Q73MC2, SYDND_TREDE;  O83950, SYDND_TREPA;  B2S4M2, SYDND_TREPS;
DR   Q112K0, SYDND_TRIEI;  Q3MGL3, SYDND_TRIV2;  C5CWX8, SYDND_VARPS;
DR   A1WHI6, SYDND_VEREI;  Q73HX6, SYDND_WOLPM;  B3CPJ5, SYDND_WOLPP;
DR   Q7M8A6, SYDND_WOLSU;  Q5GTS0, SYDND_WOLTR;  C0R2K4, SYDND_WOLWR;
DR   A7IK27, SYDND_XANP2;  Q5NPM1, SYDND_ZYMMO;
//