Due to improvement work scheduled on this server, some services may not be fully operational on Tuesday December 12 daytime (CEST
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...] View this page in https
ENZYME entry: EC 126.96.36.199
View entry in original ENZYME format
View entry in raw text format (no links)
|Nondiscriminating glutamyl-tRNA synthetase.|
|ATP + L-glutamate + tRNA(Glx) <=> AMP + diphosphate + L-glutamyl-tRNA(Glx)|
- When this enzyme acts on tRNA(Glu), it catalyzes the same reaction as
- It has, however, diminished discrimination, so that it can also form
- This relaxation of specificity has been found to result from the
absence of a loop in the tRNA that specifically recognizes the third
position of the anticodon.
- This accounts for the ability of this enzyme in, for example,
Bacillus subtilis, to recognize both tRNA(1)(Gln) (UUG anticodon) and
tRNA(Glu) (UUC anticodon) but not tRNA(2)(Gln) (CUG anticodon).
- The ability of this enzyme to recognize both tRNA(Glu) and one of the
tRNA(Gln) isoacceptors derives from their sharing a major identity
element, a hypermodified derivative of U34 (5-methylaminomethyl-2-
- The glutamyl-tRNA(Gln) is not used in protein synthesis until it is
converted by EC 188.8.131.52 into glutaminyl-tRNA(Gln).
|PRIAM enzyme-specific profiles||184.108.40.206|
|KEGG Ligand Database for Enzyme Nomenclature||220.127.116.11|
|IUBMB Enzyme Nomenclature||18.104.22.168|
|MEDLINE||Find literature relating to 22.214.171.124|
entries corresponding to 6.1.1.-
entries corresponding to 6.1.-.-
entries corresponding to 6.-.-.-