ID   6.1.1.25
DE   Lysine--tRNA(Pyl) ligase.
CA   ATP + L-lysine + tRNA(Pyl) = AMP + diphosphate + L-lysyl-tRNA(Pyl).
CC   -!- In organisms such as Methanosarcina barkeri that incorporate the
CC       modified amino acid pyrrolysine (Pyl) into certain methylamine
CC       methyltransferases, an unusual tRNA(Pyl), with a CUA anticodon,
CC       is charged directly with pyrrolysine by this class II aminoacyl--tRNA
CC       ligase.
CC   -!- The tRNA and the ligase are encoded within the same gene cluster,
CC       and the ligase does not appear to be closely related to EC 6.1.1.6.
//