ENZYME entry: EC 6.2.1.36
| Accepted Name |
| 3-hydroxypropionyl-CoA synthase.
|
| Alternative Name(s) |
| 3-hydroxypropionate--CoA ligase. |
| 3-hydroxypropionyl-CoA synthetase (AMP-forming). |
| Reaction catalysed |
| 3-hydroxypropanoate + ATP + CoA <=> 3-hydroxypropionyl-CoA + AMP + diphosphate |
| Comment(s) |
- Catalyzes a step in the 3-hydroxypropanoate/4-hydroxybutyrate cycle,
an autotrophic CO(2) fixation pathway found in some thermoacidophilic
archaea.
- The enzymes from Metallosphaera sedula and Sulfolobus tokodaii can
also use propanoate, acrylate, acetate, and butanoate as substrates,
and are thus different from EC 6.2.1.17, which does not accept
acetate or butanoate.
|
| Cross-references |
| BRENDA | 6.2.1.36 |
| EC2PDB | 6.2.1.36 |
| ExplorEnz | 6.2.1.36 |
| PRIAM enzyme-specific profiles | 6.2.1.36 |
| KEGG Ligand Database for Enzyme Nomenclature | 6.2.1.36 |
| IUBMB Enzyme Nomenclature | 6.2.1.36 |
| IntEnz | 6.2.1.36 |
| MEDLINE | Find literature relating to 6.2.1.36 |
| MetaCyc | 6.2.1.36 |
| UniProtKB/Swiss-Prot |
|
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